MHC Structure

3. Disulfide Bonds

Cysteine (thick sticks) in a 5-amino acid fragment.
C N O S (Hydrogen is not shown.)

Cystine: a disulfide bond between cysteines.

A backbone trace is superimposed.

Only the backbone trace and the disulfide bond are now shown.

For backbone traces, disulfide bonds are usually simplified to a rod connecting the cystine alpha carbons.

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Explore further the molecule(s) in this Tutorial:

Glycine: glycine.pdb in FirstGlance in Jmol. This molecule appears in Chapter 1. This molecule is not available, at least in the form shown here, from the PDB.
Quadrapeptide KAIT (from 1rog): pepb27_4.pdb in FirstGlance in Jmol. This molecule appears in Chapter 2. This molecule is not available, at least in the form shown here, from the PDB.
Disulfide bond between 2 pentapeptides (from 2ig2): s-s.pdb in FirstGlance in Jmol. This molecule appears in Chapter 3. This molecule is not available, at least in the form shown here, from the PDB.
Mouse MHC Class I (H-2K^b) with nonapeptide from Sendai virus nucleoprotein: 2vab in Proteopedia or in FirstGlance in Jmol. This molecule appears in Chapters 4, 5, 6.
Mouse MHC Class I (H-2K^b) with octapeptide from VSV nucleoprotein: 2vaa in Proteopedia or in FirstGlance in Jmol. This molecule appears in Chapter 6.
Both virus peptides, compared: pepboth.pdb in FirstGlance in Jmol. This molecule appears in Chapter 6. This molecule is not available, at least in the form shown here, from the PDB.
Human MHC Class II (HLA-DR1) with 13 amino acid peptide from influenza hemagglutinin: 1dlh in Proteopedia or in FirstGlance in Jmol. This molecule appears in Chapter 7.

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License

This Tutorial is copyright © 2010 by Eric Martz, and is licensed under a Creative Commons Attribution - Noncommercial - Share Alike 3.0 License. Copies of this Tutorial are available on request from the author, should you wish to put it on your own server, or modify the content.

History This tutorial was first developed as a RasMol Movie Script in December, 1995. In November, 1997, it was ported to a "Two Frame Chime Tutorial", and some improvements were made in early 1998. In August, 2010, it was ported to Jmol with further improvements.
[JTAT version: September 8, 2010.]