OMIM :  131550


CGAP : 77432




  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)

  • ERBB



Cell Location



Cell Type Distribution


  • Developmental expression of transforming growth factor-alpha and epidermal growth factor receptor proteins in the human pancreas and digestive tract. Hormi K, Lehy T.







  • Interaction of the neu/p185 and EGF receptor tyrosine kinases: implications for cellular transformation and tumor therapy. Dougall WC, Qian X, Greene MI.


  • Immunohistochemical examination of EGF and EGFR and c-erbB-2 is useful in forming a prognosis for pancreatic cancer patients. Yamanaka Y.



DNA Structure





  • EGFR and the p185c-neu protein serve vital roles in the transduction of differentiation,developmental, or mitogenic signaling within normal cells. Dougall WC, Qian X, Greene MI.





Gene Frequency (Tumors)


  • The immunohistochemical expressions of epidermal growth factors, epidermal growth factor receptors and c-erbB-2 oncoprotein in human pancreatic cancer. Yamanaka Y.



Ligand Binding





  • Role of growth factors in pancreatic cancer. Korc M.


  • Expression of EGF, TGF-alpha, EGFR and c-erbB2 genes and their gene products in human pancreatic carcinoma cell lines. Chen J, Liu TH.








Tumor Type