OMIM :  601231

GENECARD : FRAP1

CGAP : 338207

Cell Cycle

• FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation. Shah SA, Potter MW, Ricciardi R, Perugini RA, Callery MP.

Clinical

• Regulation of cell growth and cyclin D1 expression by the constitutively active FRAP-p70s6K pathway in human pancreatic cancer cells. Grewe M, Gansauge F, Schmid RM, Adler G, Seufferlein T.

Function

• FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation. Shah SA, Potter MW, Ricciardi R, Perugini RA, Callery MP.

• Regulation of cell growth and cyclin D1 expression by the constitutively active FRAP-p70s6K pathway in human pancreatic cancer cells. Grewe M, Gansauge F, Schmid RM, Adler G, Seufferlein T.

Oncogenicity

•  FRAP-p70s6K signaling appears to be necessary for proliferation in pancreatic cancer cells. Shah SA, Potter MW, Ricciardi R, Perugini RA, Callery MP.