OMIM :  604724

GENECARD : HPSE

CGAP : 44227

Biochemical type         

• The human endoglycosidase heparanase (hpa) degrades heparan-sulfate Proteoglycans… Koliopanos A, Friess H, Kleeff J, Shi X, Liao Q, Pecker I, Vlodavsky I, Zimmermann A, Buchler MW.

Function          

• The human endoglycosidase heparanase (hpa) degrades heparan-sulfate Proteoglycans…. Koliopanos A, Friess H, Kleeff J, Shi X, Liao Q, Pecker I, Vlodavsky I, Zimmermann A, Buchler MW.

Oncogenicity

• Hpa overexpression in human pancreatic cancers facilitates cancer cell invasion. Koliopanos A, Friess H, Kleeff J, Shi X, Liao Q, Pecker I, Vlodavsky I, Zimmermann A, Buchler MW.