Cell Cycle

• Id2 specifically alters regulation of the cell cycle by tumor suppressor proteins. Lasorella A, Iavarone A, Israel MA.  

Chromosome, Human

• Chromosomal assignment of human ID1 and ID2 genes.Mathew S, Chen W, Murty VV, Benezra R, Chaganti RS.

Function

• Id2 expression increases with differentiation of human myeloid cells. Ishiguro A, Spirin KS, Shiohara M, Tobler A, Gombart AF, Israel MA, Norton JD, Koeffler HP.  

Oncogenicity

• The helix-loop-helix protein Id2 is overexpressed in human pancreatic cancer.Kleeff J, Ishiwata T, Friess H, Buchler MW, Israel MA, Korc M.

• Id-1 and Id-2 are overexpressed in pancreatic cancer.Maruyama H, Kleeff J, Wildi S, Friess H, Buchler MW, Israel MA, Korc M.