[BiO BB] Alignment of profiles

Dennis Livesay drlivesay at csupomona.edu
Mon Aug 26 20:06:09 EDT 2002


Hi,

I'm attempting to globally align two profiles.  I need to determine a score
for the overall similarity between the two profiles that won't be biased by
the size of the initial profiles.  Meaning, simply adding up the column scores
from the final MSA won't suffice because the larger of the two initial
profiles would have a larger influence on the final score.  Any help?

Thanks,
Dennis

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Dr. Dennis Livesay
Department of Chemistry
Cal Poly, Pomona
phone: 909-869-4409
email: drlivesay at csupomona.edu




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