[BiO BB] query
p.pagel at gsf.de
Tue Nov 26 04:54:02 EST 2002
> Is there any way to find the genes involved in particular biological
> process. for eg. apoptosis.
Depends. Not in the sense that some magic algorithm derives the function
directly fom the sequence.
BUT: There are manually annotated genomes which means that human expert
curators have tried to assign a functional category to each gene of the
organism. Our institute provides such data for Saccharomyces cerevisiae
(and a few other organisms):
watch out for FUNCAT (= functional category). Explanations here:
You can find the same kind of analysis for a number of other genomes
here (http://pedant.gsf.de). For most of them the FUNCATs were assigned
by the computer based on homology - manual annotations can be identified
by the "MANUAL FUNCAT" link (as opposed to the "AUTOMATIC FUNCAT").
Another aproach you should look at is Gene Ontology:
Dr. Philipp Pagel Tel. +49-89-3187-3675
Institute for Bioinformatics / MIPS Fax. +49-89-3187-3585
GSF - National Research Center for Environment and Health
Ingolstaedter Landstrasse 1
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