[BiO BB] About clustering genes to gene family

[Zheng Fu]

Hi everyone,

Does anyone know how to clustering genes to a gene family based on the
sequence alignments.
For two genes, we can define a threshold to seperate the homolog and
non-homolog. But for three or more genes,how to define the homologs?(Such
as Gene A and Gene B has high alignment score, A and C also has high sore,
but B and C doesn't have high socre, can we say ABC are homologs?

Thank you.

Carol

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