[BiO BB] About clustering genes to gene family

Martin Gollery mgollery at unr.edu
Thu Aug 7 14:44:03 EDT 2003

Hi Carol,
Take a look at the D2_cluster program by Hide, Burke, and Davidson. I don't 
recall the journal. The program is available free from Biotique for academics.


Quoting Zheng Fu <zfu at cs.ucr.edu>:

> Hi everyone,
> Does anyone know how to clustering genes to a gene family based on the
> sequence alignments.
> For two genes, we can define a threshold to seperate the homolog and
> non-homolog. But for three or more genes,how to define the homologs?(Such
> as Gene A and Gene B has high alignment score, A and C also has high sore,
> but B and C doesn't have high socre, can we say ABC are homologs?
> Thank you.
> Carol
> -- 
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Martin Gollery
Associate Director of Bioinformatics
University of Nevada at Reno
Dept. of Biochemistry / MS330
New phone number! 775-784-7042

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