[BiO BB] protein clustering threshold

Bossers, Alex Alex.Bossers at wur.nl
Tue Feb 10 02:04:25 EST 2004


And then there were...... prions. Proteins with the same primary amino
acid sequence but different conformations and functions....... Most of
you know of prions and prion proteins in infectious diseases like
mad-cow disease (BSE) and CJD in humans.
Some info at: http://home.hccnet.nl/a.bossers/Thesis.htm


> -----Oorspronkelijk bericht-----
> Van: bio_bulletin_board-admin at bioinformatics.org
> admin at bioinformatics.org] Namens Hongyu Zhang
> Verzonden: maandag 9 februari 2004 20:27
> Aan: bio_bulletin_board at bioinformatics.org
> Onderwerp: [BiO BB] protein clustering threshold
> Does anyone have examples of two proteins with >90%
> sequence identity have differenct functions? I need it as a
> proof to cluster a protein sequence library.
> Thanks!
> Hongyu
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