[BiO BB] protein clustering threshold

Iddo Friedberg idoerg at burnham.org
Tue Feb 10 12:20:43 EST 2004


Not to answer your question directly, 
just to add confusion:

How about the same protein which performs different functions?
Crystallins
are an example of a protease which, in the eye lens, serves as a
transparent buffer.

There are other such "moonlighting proteins" look at:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12902157&dopt=Abstract

./I

--
Iddo Friedberg, Ph.D.
The Burnham Institute
10901 N. Torrey Pines Rd.
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http://ffas.ljcrf.edu/~iddo

On Fri, 6 Feb 2004, Hongyu Zhang wrote:

> Does anyone have examples of two proteins with >90%
> identity have differenct functions? I need it as a
> proof to cluster a protein sequence library.
> 
> Thanks!
> 
> Hongyu
> 
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