[BiO BB] computational mutagenesis
idoerg at burnham.org
Wed Mar 10 13:45:59 EST 2004
Andrei Sali has been doing some work with exending MODELLER to include
protein complexes. You might want to check his site to see what's new on
Dana Reichmann wrote:
> Iddo hi,
> thanks for the suggestion, i'll check it,
> I am more interesting on evaluation of changes upon mutation
> (structure and thermodynamic changes) when the structure of a wild
> type complex is known. Something similar to FOLDEFF program (from
> L.Serrano group) or Rosetta from D. Baker.
> On Mar 10, 2004, at 7:50 PM, Iddo Friedberg wrote:
>> Have you looked at the CAPRI site (http://capri.ebi.ac.uk/)
>> and papers in Proteins?
>> Dana Reichmann wrote:
>>> Hi all,
>>> I am looking for good programs and algorithms for computational
>>> mutagenesis that can define hot spots in *protein-protein
>>> *interactions. I am interesting in different approach such as
>>> thermodynamical, structural etc. I want to understand what kind of
>>> approach are better, what is maximal prediction % of each.
>>> Thanks a lot,
>> Iddo Friedberg, Ph.D.
>> The Burnham Institute
>> 10901 N. Torrey Pines Rd.
>> La Jolla, CA 92037
>> Tel: +1 (858) 646 3100 x3516
>> Fax: +1 (858) 713 9930
> BiO_Bulletin_Board maillist - BiO_Bulletin_Board at bioinformatics.org
Iddo Friedberg, Ph.D.
The Burnham Institute
10901 N. Torrey Pines Rd.
La Jolla, CA 92037
Tel: (858) 646 3100 x3516
Fax: (858) 646 3171
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