[BiO BB] Structural genomics and PDB growth?

Dan Bolser dmb at mrc-dunn.cam.ac.uk
Tue Sep 7 12:20:59 EDT 2004


On Wed, 11 Aug 2004, Iddo Friedberg wrote:

>
>--- Dan Bolser <dmb at mrc-dunn.cam.ac.uk> wrote:
>
>> On Mon, 9 Aug 2004, Iddo Friedberg wrote:
>> 
>> >Hi Dan,
>> >
>> >For your first question:
>> >
>> >We published something in PSB'04
>> >
>> >http://helix-web.stanford.edu/psb04/bourne.pdf
>> 
>> Cheers.
>> 
>> >
>> >I don't know about definitive, but it is fairly exhaustive, based
>> on
>> >data which was up-to-date for summer 2003.
>> >
>> >PDB will keep growing as long as crystallographers/NMR people have
>> >jobs and have families to feed. Future growth rate, as always, is
>> >estimated by extrapolation. However, come the technological
>> >breakthrough whcih will enable faster solutions for membrane
>> >proteins, the growth rate will probably increase :)
>> 
>> That is the thing, but is the rate of increase increasing?
>
>
>I'm not sure by what you mean by "an increasing rate of increase".
>PDB growth is exponential. 

What is the exponent? Any citation on this?

When I say 'increasing increase' I mean (I think) an increasing exponent
over time, something like a double exponential.

This looks interesting...

http://www.npaci.edu/online/v6.4/pdb.predict.html

http://cubic.bioc.columbia.edu/papers/1998_marrying/paper.html

I haven't had time to look in detail at the replies I got from this query,
so thanks for those. I will try to summarize them when I do.

Cheers,
Dan.


>
>./I
>
>> 
>> >Cheers,
>> >
>> >Iddo
>> >
>> >
>> >
>> >--- Dan Bolser <dmb at mrc-dunn.cam.ac.uk> wrote:
>> >
>> >> 
>> >> Can anyone point me at definative literature for estimates of
>> PDB
>> >> growth
>> >> and the impact of structural genomics?
>> >> 
>> >> What evidence do we have that the PDB will keep growing? What is
>> >> the best
>> >> current estimate of that growth rate?
>> >> 
>> >> Cheers,
>> >> Dan.
>> >> 
>> >> 
>> >> _______________________________________________
>> >> BiO_Bulletin_Board maillist  - 
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>> >> 
>> >
>> >
>> >=====
>> >--
>> >Iddo Friedberg                   
>> >The Burnham Institute
>> >10901 N. Torrey Pines Rd.
>> >La Jolla, CA, 92037
>> >USA 
>> >T: (858) 646 3100 x3516
>> >http://ffas.ljcrf.edu/~iddo
>> >
>> >
>> >		
>> >__________________________________
>>
>
>=====
>--
>Iddo Friedberg                   
>The Burnham Institute
>10901 N. Torrey Pines Rd.
>La Jolla, CA, 92037
>USA 
>T: (858) 646 3100 x3516
>http://ffas.ljcrf.edu/~iddo
>
>
>	
>		
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