[BiO BB] Function Search

Daniel Amelang danny at amelang.net
Fri Mar 18 16:07:54 EST 2005


This is one of the first options to come to mind. And one of the more 
popular.

http://hmmer.wustl.edu/
http://pfam.wustl.edu/hmmsearch.shtml

Dan

Chris Moy wrote:

> Hello All,
>
> I am in the process of trying to mine some of the data to see if there 
> is a possible function for a protein of interest. I have  been 
> performing PSI-Blast with a whole set of organisms and the process is 
> quickly becoming a little overwhelming in terms of trying to make 
> sense of all the data. Does anyone have any suggestions about a 
> systematic way to get a handle on possible functions for a region of 
> my protein.  Right now I have limited my search to 300 residues that 
> are just a small portion of the protein of interest. Suggestions 
> regarding the use of HMMRs and PSSMs are welcome!
>
> Chris
>
>
>
> Chris Moy
> University of Pennsylvania - Department of Ophthalmology/Genetics
> 215-898-9838
> moyc at mail.med.upenn.edu
>
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