[BiO BB] Reaction with missing EC number?

Dan Bolser dmb at mrc-dunn.cam.ac.uk
Tue Oct 11 13:37:30 EDT 2005

Hi, looking at Kegg (Ligand) I find the following reaction...

succinyl-CoA:acetyl-CoA C-succinyltransferase
L-Alanine + Acetyl-CoA <=> 2-Amino-4-oxopentanoic acid + CoA

However, the EC number for this reaction appears to be "EC 2.3.1.-", 
i.e. not a proper EC number. The weird thing is that this EC number *is* 
used in the Kegg Valine, leucine and isoleucine degradation pathway.

I thought one way that this could come about is if the reaction itself 
hasn't yet been assigned an EC number but is otherwise OK, and is used 
with the 'temporary/approximate' EC number in place of the yet to be 
assigned (correct) one.

Anybody know if that is correct?

Seems strange to see an approximate EC number in a step of a pathway 
with known inputs and outputs. Although looking at the data it doesn't 
appear to be uncommon.

Anyone have any information on the use of these approximate numbers at KEGG?


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