[BiO BB] Reactome version 18 released!
Reactome-Knowledgebase at reactome.org
Reactome-Knowledgebase at reactome.org
Thu Aug 3 10:39:31 EDT 2006
The Reactome Knowledgebase team (Lincoln Stein's group at CSHL and
Ewan Birney's group at European Bioinformatics Institute) is proud
to announce the release of Reactome Version 18, accessible at
http://www.reactome.org!
Reactome is a curated knowledgebase of biological processes in
humans. It covers processes ranging from basic pathways of metabolism
to complex events such as hormonal signaling and apoptosis. The
information in Reactome is provided by expert bench biologists, and
edited and managed as a relational database by the Reactome staff.
New material is peer-reviewed and revised as necessary before
publication to the web. Reactome entries are linked to corresponding
ones in NCBI EntrezGene, RefSeq, OMIM, Ensembl genome annotations,
UCSC Genome Browser, KEGG, ChEBI and Gene Ontology (GO).
New modules include the signaling cascade mediated by Toll-like
receptor 2, Maintenance of Telomeres, Entry and Binding under HIV
Life Cycle and the pathways of Complement Activation. Reactions and
pathways chosen by the user are now highlighted prominently in the
reaction map at the top of each web page. Updated release statistics
and the Editorial Calendar are available.
A new web display feature allows the user to choose the focus species
annotations - curated (for human) and electronically inferred (for 22
other species). Stable identifiers have been introduced to facilitate
the tracking of data objects over successive releases of Reactome.
As before, Reactome data can be exported in SMBL, Protégé, and BioPAX
level 2 formats.
Like everything in Reactome, these downloaded and exported materials
can be reused and redistributed freely. For questions and comments
please reply to this message or write to help at reactome.org
-Gopal Gopinathrao
Reactome, CSHL
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