[BiO BB] How to calculate the value of K and Lambda for two sequence alignment

[shohag md]

Hi Everybody



Using Smith Waterman algorithm I want to align two sequences. Aftet that I
want to calculate the expectation value. For calculating the expectation
value we know that



E = Kmn e -lx



But how can I calculate the value of K and l .


Is there any formula that can help me to calculate the value of K and l ,  and
then the expectation value.

Thanking all in advance

Shoyaib
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