[BiO BB] calculate internal thermodynamic stability profiles

hongyan wang hongyanww at yahoo.com
Mon Mar 13 12:08:12 EST 2006

  Hi, All,
  Does any body know any free internet-based  software that can give an analysis of internal thermodynamic stability profiles for siRNA/shRNA . I need to assess  the stability of the First Four nucleotides on either end of some siRNA -- perfect matched and mismatched.  S-fold won't give the profile of the end nucleotides and mismatched siRNAs. Thanks very much in advance.
  Hongyan Wang

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