[BiO BB] BLOCKS motifs and protein protein interactions
Boris Steipe
boris.steipe at utoronto.ca
Wed Sep 17 10:55:27 EDT 2008
No, that inference is not generally possible. Only if the proteins
are very(!) closely related.
Google "interologs" for background on the limits of annotation
transfer for interacting proteins.
B.
On 15-Sep-07, at 6:57 PM, Mahmoud Elhefnawi wrote:
> Dear all,
>
> I was wandering if BLOCKS database homology hits with significant e
> values habe been correlated before to infer protein protein
> interactions?
>
> i.e" if protein A interacts with protein B, and protein C has a
> significant match with protein B, then protein C also interacts
> with protein A???
>
> Best,
> Mahmoud
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