[BiO BB] WORKSHOP ON CIRCUIT & MOLECULAR ARCHITECTURE OF THE VERTEBRATE BRAIN, JUNE 17 – 29, 2010, Application deadline: April 30, 2010

[Neuro Informatics]

*ANNOUNCING A NEW CSH WORKSHOP ON CIRCUIT & MOLECULAR ARCHITECTURE OF THE
VERTEBRATE BRAIN*



Dear Colleague:





*WORKSHOP ON CIRCUIT & MOLECULAR ARCHITECTURE OF THE VERTEBRATE
BRAIN*<http://meetings.cshl.edu/courses/c-circuits10.shtml>
**

*JUNE 17 – 29, 2010*

*Application deadline:  April 30, 2010*

Instructors: Partha Mitra, Kathy Rockland & Z. Josh Huang

*Please pass this along to colleagues or members of your laboratory or group
who may benefit from this training. *

In comparison with complete reference genomes now available for multiple
species, our knowledge about the neuronal and circuit architecture of the
vertebrate nervous systems is relatively sparse. However, this situation is
rapidly changing, enabled by technical advances as well as resurgent and
widespread interest in the neuroscientific community in mapping out neural
circuitry at unprecedented scales, ranging from the reconstruction of local
micro-circuits to the mapping of brain-wide meso-circuits. This circuit
architecture naturally and logically complements the molecular architecture
as delineated by the mapping of brain-wide gene expression patterns.
Experimental efforts are under way in multiple species, promising to advance
our knowledge of the wiring logic of the vertebrate brain. This will
fundamentally impact our understanding of brain function and evolution, and
also play an essential role in understanding pathological changes in
circuitry that underlie neurological and neuropsychiatric disorders.



This two week workshop will bring together classical neuroanatomical
approaches along with the new techniques that are enabling a new generation
of neuroanatomical research into the circuit and molecular architecture of
the vertebrate brain. The workshop will have three main components:
classical, molecular and computational neuroanatomy. An experimental
component of the workshop will involve injection based tract tracing in the
mouse, employing classical and viral tracer substances, in wild type and
transgenic mice. Lectures will cover classical (tracer injections,
sectioning, histochemistry, imaging) and molecular (genetic engineering of
mice as well as viral tracers, optogenetic probing of circuits) techniques.
Material will be presented by simultaneous viewing of slides under light
microscopy as well as digital images, including an in-depth orientation to
internet resources. The computational component will involve hands on
algorithmic analysis and interpretation of digital neuroanatomical data
sets, from both EM and light microscopy. Species covered will include
rodents, human and nonhuman primates, with special lectures on other
vertebrate lineages.



Speakers include: John Allman, David Amaral, Katrin Amunts, Jason Bohland,
Mitya Cklovskii, Karl Deisseroth, Bruce Fischl , Mike Hawrylycz , Mark
Henkelman, Harvey Karten , David Kleinfeld, Kevan Martin, Marcello Rosa, Joe
Safdieh , Cliff Saper , Nenad Sestan, Karel Svoboda , Larry Swanson, Menno
Witter & Hongkui Zeng



Partial scholarships may be available to offset tuition, room and board
costs based on stated need (apply in writing).



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