[BiO BB] protein merge
naveejoshi at gmail.com
Mon Mar 15 16:07:36 EDT 2010
Hi think you are trying to study the gene fusion event or the
duplication of a specific part of protein due to gene duplication.. Maybe
you can try reading some papers on the phenomenon of gene fusion. try going
for a review paper as they list all the important techniques ans
also software to analyse such instances which people have used throughout
the years ..
On Tue, Mar 16, 2010 at 6:21 AM, Dan Bolser <dan.bolser at gmail.com> wrote:
> Isn't this just sequence (or structure) alignment?
> The consensus would then be the merged sequence.
> You should be able to find lots of alignment tools out there.
> On 15 March 2010 15:57, Rafik Ouerchefani <rafik at ubuntu.com> wrote:
> > Hello,
> > I'm looking for a software that can merge two proteins with a shared
> > (given .pdb files).
> > With sequences it would be like this :
> > seq 1 : MSARIATRRRDKKARRKLQ*ELGATRLVVHRT*
> > seq 2 : *ELGATRLVVHRT*PRHIYAPNGSEVLVQVIAA
> > result : MSARIATRRRDKKARRKLQ*ELGATRLVVHRT*PRHIYAPNGSEVLVQVIAA
> > These two sequences have a common sequence ELGATRLVVHRT (end of the first
> > and beginning of the second). It's easy with sequences but I have to do
> > with 3D structures. I have the 3D structures of both sequences 1 and 2.
> > Thanks,
> > - Rafik
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