Lance, > Does anyone know of an > open source blast-for-cluster package that would run under this > cluster management suite or is there a > commercial package you are already running that you think is > worthwhile??? You should consider Paracel BLAST, http://www.paracel.com/products/paracel_blast.html It's parallel Blast software for Linux and Sparc clusters, with built-in queueing and scheduling software. We've made extensive algorithmic modifications for enhanced support of large cluster systems, large databases, large query sequences, etc. Evaluation copies are available. As Chris Dagdigian mentioned, Paracel also offers the GeneMatcher2 system for hardware acceleration of dynamic programming searches like Smith Waterman, HMM, and GeneWise. See http://www.paracel.com/products/gm2.html for more information. Marc Rieffel Paracel marc@paracel.com 626-744-2080