> Can someone out there with a OS X machine see if it really is limited to > 2 GB files? This, I can do now. Running on a G4 Itanium laptop *single* processor with 1GB of RAM. Mac OS X version 10.1.4. [localhost:~] cdwan% yes > foo.txt ...in another shell...after trip upstairs for a glass of water... [localhost:~] cdwan% ls -l ... -rw-r--r-- 1 cdwan staff 3486162944 May 24 17:22 foo.txt ... So, in tcsh (per previous shell-related conversation) the redirection operators look good. A quick test of 'cat' and 'wc' also failed to dump core...so we might be in good shape. I'll pull down some bigger files (from NCBI) and try to break more pieces of it while I'm sitting on a plane this weekend. -Chris Dwan