> Applications at this stage include all of the biotools ported to Mac OS= X > by the BioTeam ( http://bioteam.net), such as Altivec optimized BLAST, > HMMER, FASTA and Clustal and the EMBOSS suite. Hi Doc ! I have some questions. We had 6 CPUs (3 X Serve running Mac OS X (I think= 10)) and the performance with optimized BLAST was not good at all. It was so s= lowly=20 againts a Power Edge DELL (one to one, and cluster to cluster performace= ).=20 So i want to ask you, what are the options used to BLAST to run ? could y= ou=20 say it to me ? > As an example, of performance, I ran a set of 3600 ESTs against Swisspr= ot > (BLASTX) using all 8 cpus and the job ran in about 45 minutes. The sam= e This is really fast ! I ran a set of 600 ESTs using BLASTN with "nt" data= base=20 and the job ran about 10 minutes (10 CPUs Power Edge) .. If I add my 3=20 Xserver to the cluster .. the time increases for the same job (?) .. I do= n't=20 understand. > memory machine), but my gut feeling is that the Xserve cluster is runni= ng > significantly faster. We are now running the Xserve without MAC OS X (I don't like windows) .. = I=20 have installed YellowDog for PPC .. and this works fine .. I compiled the= =20 ncbi-blast and it's works ! .. but de performance are still bad to me, so= ..=20 you can try YellowDog and XFree86 window enviroment :-) > Dave Im not contributing to this list, better I shut up myself -- Sergio Ahumada N san@inf.utfsm.cl