[Bioclusters] mpiBLAST 1.2.0

Jason Gans bioclusters@bioinformatics.org
Tue, 18 Nov 2003 17:46:56 -0500


The mpiBLAST development team is pleased to announce the 
availability of mpiBLAST 1.2.0. New features in this release
include:

* Alignments are output for translated searches.
* Incremental database updates.
* Distributed sequence lookup during output formatting.
* Commandline options now match the latest version of NCBI-BLAST.
* Scripts are provided to interface mpiBLAST with the NCBI web front
  end via the PBS scheduling system.
  
mpiBLAST is a parallelization of NCBI BLAST that replaces formatdb and 
blastall with versions that use MPI to execute in parallel on a cluster 
of computers. There are two primary advantages to using mpiBLAST versus 
traditional BLAST. First, mpiBLAST splits the database across each node 
in the cluster. Because each node's segment of the database is smaller 
it can usually reside in the buffer-cache, yielding a significant
speedup 
due to the reduction of costly disk I/O. Second, because interprocessor 
communication demands are low, BLAST users can efficiently use low-cost 
Beowulf clusters . 

Source code for both Unix and Windows is freely available at
http://mpiblast.lanl.gov

Please direct questions and bug reports to the sourceforge discussion
board at
http://sourceforge.net/projects/mpiblast