Hi Steve: The choice of switch fabric is largely determined by the application and use case mix. For codes requiring low latency network fabric such as electronic structure codes, various molecular dynamics, and whatnot else, you would be looking at one of the low latency high bandwidth systems. For more general applications, and trivial/embarrassingly parallel work, you could go with a higher latency fabric. Fabric topology is also important, though for this size, most folks aim towards fat trees or simple switch connected with no hierarchies. Since you will be going pure gigabit, I might recommend you look at some of the switches with better backplane bandwidth and latency characteristics. The HP Procurve 4108gl are modular, and you can add the J4908A 20 port gigabit module (6 to cover your needs). It wont be cheap, but it will work nicely. The Foundry's are good choices as well. I would avoid putting a Cisco in a cluster. One of the nicer aspects of the low latency gigabit connections is the ability to use TCP offload cards. If you really need low latency interconnects over all or a portion of your system, the offload adapters may benefit some workloads. As always, it is a cost-benefit analysis. (disclosure: my company designs/integrates clusters like this, so my comments reflect our biases) Joe Steve wrote: > I'm putting together a general lifescience based cluster (software > ranging from docking apps. to blast). Its going to consist of > approximately 100 nodes, including 2 head nodes. All nodes will be > connected through GIGE, and we will not be using high speed > interconnects. > > In the past I've used Cisco switches (4000 and 6000 series), stable, > reliable and costly. > Does anyone have any recommendations? I've had mixed reviews about > Extreme, so I'd be interested in Foundy, Procurve or any systems > people may have had success with. > > Cheers, > > Steve -- Joseph Landman, Ph.D Scalable Informatics LLC, email: landman@scalableinformatics.com web : http://www.scalableinformatics.com phone: +1 734 612 4615