mpiBLAST 1.3.0 has (finally) been released. It incorporates several major design changes that improve reliablilty, performance, and accuracy. Key enhancements are: - utilizes latest NCBI Toolbox (Oct 20, 2004) - E-value scores are exact and identical to scores reported by NCBI BLAST by using both the effective query and effective database lengths. (It is necessary/required to patch the NCBI Toolbox before compilation) - Database pipelining speeds up database distribution by limiting access to shared filesystem. Number of concurrent accesses is a run-time option (--concurrent). - Results pipelining reduces memory requirements for large query sets. - Database distribution can occur through cp, scp, or rcp system calls, through MPI function calls (MPI_Send/MPI_Recv), or not at all if you choose to use the shared filesystem as local storage. It is a runtime option (--copy-via). mpiBLAST version 1.3.0 was a long time in coming, but is the fastest, most exact, and most stable version of mpiBLAST yet. Download it here: http://mpiblast.lanl.gov - the mpiBLAST team