Peter, Chris is right - other important factors are what infrastructure you have at your site: Do you have an available system administrator, and for which OS? Do you have good service contracts with a specific hw vendor? Do you need to integrate with your site's IT infrastructure? Additionaly, the setup depends on the volume of clients you plan to serve, their profiles (anyone from the web, registered individuals, or only internal use); The level of service and availability (what uptime will you need; Do you need a test environment to run in parallel with a production environment). The best thing you can do is get an expert to analyze your requirments, or if you can't pay - get free advice from a hw vendor (the quality of which depends on the strength of your relationship with the vendor). Regards, -- Ran Rubinstein, Bioinformatics Consultant Faculty of Medicine, Hebrew University, Ein Karem, Israel Tel +972-2-6757906 Fax +972-2-6758992 ---------------------------------------------------------------- This message was sent using IMP, the Internet Messaging Program.