Hi Malay: > Oops I forgot to mention the third option. This is for > production machine for very high end scaling up and requires > ample amount of disc space in each node. This is to have each > node it's local copy of database. And use input spitting > through SGE. This the best way to scale up to ~1000 jobs at a > time. But because of database maintanance issue, this method > is advisable of for dedicated BLAST farm. You meant 'input splitting' right? And how would you accomplish that using SGE? By scripting it in your job script? Thanks, Bernard