<forwarded: RPMs will be available soon from downloads.scalableinformatics.com> We are pleased to announce the availability of BLAST 2.2.12. Binaries are available from the BLAST download page. Notes for the 2.2.12 release Bug fixes * The megablast -s option was not functioning; fixed in megablast.c 6.169. * Multithreaded megablast was not functioning; fixed in megablast.c 6.133. * Selenocysteine residues were not scored properly in protein alignments; fixed in blast_kappa.c 1.57 & 1.58, kappa.c 6.62 & 6.63. * Ungapped blastpgp was not functioning correctly and was deemed unnecessary; the -g option was removed in blastpgp.c 6.131. * formatrpsdb was not working properly; fixed in formatrpsdb.c 1.18. Improvements * Megablast, rpsblast, and bl2seq now use the new BLAST engine codebase by default. This can result in significantly faster searches. * Discontiguous megablast is now substantially faster. * formatdb can now incorporate taxonomic information into BLAST databases by using the -T option. * fastacmd can now dump accessions by using the -D 3 option. * New compositional score adjustment algorithms are implemented in blastpgp; see Bioinformatics 21:902-911, 2005 for details. If you have any questions please contact blast-help at ncbi.nlm.nih.gov. -- Joseph Landman, Ph.D Founder and CEO Scalable Informatics LLC, email: landman at scalableinformatics.com web : http://www.scalableinformatics.com phone: +1 734 786 8423 fax : +1 734 786 8452 cell : +1 734 612 4615