Dear bio-cluster users, I'm working on general methods to use Grid systems, esp. US TeraGrid as a replacement for maintaining your own local clusters in genome analyses. The general idea is to create a set of shared protocols and middleware such that many groups can use shared grid systems for genome analyses, rather than go thru the maintenance hassles of setting up and maintaining each one's own. The Generic Model Organism Database project (www.gmod.org) will be a repository for this shared work, and we hope to have common bioinformatics tools and data sets installed for genome work at TeraGrid sites E.g. like NC BioPortal, http://www.ncbiogrid.org/, maybe in collaboration with them -- their work is now mostly provides a web interface via Pise-Emboss-etc with bio-datasets at TeraGrid sites. For genome informatics, we expect to use mostly command-line type access. See here for genome assembly and analyses on TeraGrid: http://iubio.bio.indiana.edu/biogrid/genome-on-teragrid-poster.html http://iubio.bio.indiana.edu/biogrid/teragrid-genomics06-proposal.pdf Anyone interested in using such methods, please feel free to contact me. - Don Gilbert -- d.gilbert--bioinformatics--indiana-u--bloomington-in-47405 -- gilbertd at indiana.edu -- http://marmot.bio.indiana.edu/