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<DIV><FONT face=Arial size=2><SPAN class=268361823-29112005>Hi
Ethan,</SPAN></FONT></DIV>
<DIV><FONT face=Arial size=2><SPAN
class=268361823-29112005></SPAN></FONT> </DIV>
<DIV><!--StartFragment --><FONT face=Arial size=2><SPAN
class=268361823-29112005>We at the Genome Sciences Centre have developed a
software tool called DiscoverySpace which can help you assign sub cellular
localization to your Refseq gene list.</SPAN></FONT></DIV>
<DIV><FONT face=Arial size=2><SPAN
class=268361823-29112005></SPAN></FONT> </DIV>
<DIV><FONT face=Arial size=2><SPAN class=268361823-29112005>Although we don't
have the ability, as yet, to map genes directly to protein
localization, our application does allow you to assign the list
to both PSORT and PAGOSUB, both of which were mentioned earlier by Jenn
Grady. In the case of PSORT we store the pre-computed results for all of the
Refseq proteins, which makes the assignments very quick.
</SPAN></FONT></DIV>
<DIV><FONT face=Arial size=2><SPAN
class=268361823-29112005></SPAN></FONT> </DIV>
<DIV><FONT face=Arial size=2><SPAN class=268361823-29112005>Our application
provides a user interface to over 10 of the more frequently used
biological databases in the public domain which we have integrated into one
large 'warehouse'. Some of the databases we support are GO, SwissProt,
Refseq, Ensembl and MGC.</SPAN></FONT></DIV>
<DIV><FONT face=Arial size=2><SPAN
class=268361823-29112005></SPAN></FONT> </DIV>
<DIV><FONT face=Arial size=2><SPAN class=268361823-29112005>More information
about DiscoverySpace including primers, tutorials and downloads can be found
at:</SPAN></FONT></DIV>
<DIV><SPAN class=268361823-29112005><U><FONT color=#00ffee><A
href="http://www.bcgsc.ca/bioinfo/software/discoveryspace/">http://www.bcgsc.ca/bioinfo/software/discoveryspace/</A></FONT></U>
</SPAN></DIV>
<DIV><SPAN class=268361823-29112005><U><FONT
color=#00ffee></FONT></U></SPAN> </DIV>
<DIV><SPAN class=268361823-29112005><FONT face=Arial size=2>or feel free to
contact us at </FONT><A href="mailto:discoveryspace-support@bcgsc.ca"><FONT
face=Arial color=#000000
size=2>discoveryspace-support@bcgsc.ca</FONT></A></SPAN></DIV>
<DIV><SPAN class=268361823-29112005><U><FONT
color=#00ffee></FONT></U></SPAN> </DIV>
<DIV><SPAN class=268361823-29112005><FONT face=Arial size=2>Best
Regards</FONT></SPAN></DIV>
<DIV><SPAN class=268361823-29112005><FONT face=Arial
size=2></FONT></SPAN> </DIV>
<DIV><SPAN class=268361823-29112005><FONT face=Arial size=2>Richard
Varhol</FONT></SPAN></DIV>
<DIV><SPAN class=268361823-29112005><FONT face=Arial
size=2></FONT></SPAN> </DIV>
<DIV><SPAN class=268361823-29112005><FONT face=Arial size=1>Assistant
Bioinformatics Coordinator</FONT></SPAN></DIV>
<DIV><SPAN class=268361823-29112005><FONT face=Arial size=1>Genome Sciences
Centre</FONT></SPAN></DIV>
<DIV><SPAN class=268361823-29112005><FONT face=Arial size=1>Vancouver
Canada</FONT></SPAN></DIV></BODY></HTML>