> >My web surfing showed that ZEND( part of PHP ) can >make calls to C > programs like CIFLIB but the may need >to be recompiled with ZEND stuff. I think you refer to the ability to extend the php language with your own (c) code (http://www.php.net/manual/en/zend.php). Disadvantage of doing this is that everyone who wants to use these extensions will have to recompile php (admitted, php is one of the easiest compiles I have encountered, but this does not seem like a good idea for a bioinformatics library). > There are criticisms of PHP being unsuitable for > computationally-intensive tasks because it is an interpreted > language. Do you think the Zend > compiler is the answer to this? Does it produce > code whose speed is comparable to that produced > by a C/C++ compiler? Yes, since it is code produces by a C compiler. B.t.w. there is a nice (and free) accelerator for php available (www.php-accelerator.co.uk/). It caches (compiled) php code on disk and in RAM. I have it installed on our server and it works flawlessly. Best, Nico