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<font size=3>At 06:34 AM 10/25/04, you wrote:<br><br>
<blockquote type=cite class=cite cite="">Dear Richard Blake,<br>
I am using Meltsim in order to study the dependance of dna melting curves
with respect to<br>
loop exponent and cooperativity parameter.<br>
I would like to know where they can be modified in the code.<br>
Many thanks and best regards,<br><br>
Taofiq Paraiso<br><br>
<br>
J.W. Bizzaro wrote:<br><br>
<blockquote type=cite class=cite cite="">Hi Taofiq.<br><br>
Questions about the algorithm will be best answered by Richard
Blake.<br>
Please send your question to <meltsim@bioinformatics.org> asking
him<br>
specifically.<br><br>
Do you have Enrico Carlon's email address?<br><br>
Cheers.<br>
Jeff<br><br>
Taofiq Paraiso wrote:<br><br>
<blockquote type=cite class=cite cite="">Hi Jeff,<br><br>
Finally my administrator could modify the code in order to run it under
Linux.<br>
We don't have the user interface any more but this is not a
problem.<br>
Now I would like to modify the loop exponent and cooperativity
parameters, which are<br>
called alpha and sigma in the code respectively.<br>
I understood that the value of alpha was assumed to be 1.75 (alpha is not
initialized in the code).<br>
The value of sigma is calculated according to initial and the final
values of sigma, which seem<br>
to be in relation with the initial and final temperature. Could you
confirm if I understood well?<br><br>
Best regards, Tao<br><br>
ps: I just received an email from Enrico Carlon, who told me that he has
a C version of meltsim.</blockquote><br>
</blockquote><br><br>
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