[Molvis-list] Recent MolVis articles in BAMBEd
Eric Martz
emartz at microbio.umass.edu
Wed Sep 6 17:34:20 EDT 2006
The journal "Biochemical and Molecular Biology Education" (BAMBEd,
http://www.bambed.org/ www required) continues to grow and thrive under the
editorship of Don and Judy Voet.
The May/June issue includes "A new three-dimensional educational model kit
for building DNA and RNA molecules: development and evaluation", which
describes injection-molded plastic models with attention to pedagogically
important detail. The authors are in Brazil and I found no mention of
whether their models are available for purchase.
The July/August issue contains three articles relevant to MolVis.
Tim Herman and others contribute "Tactile teaching, exploring protein
structure/function using physical models". They make a compelling case for
the impact of physical models in learning. They have led exciting model
designing collaborations between educators/students and researchers
reporting cutting edge molecular structures. They have initiated impressive
model-building challenges for the Science Olympiad competition. A cut-away
spacefilled model of the active site of acetylcholinesterase combats the
mis-impression (from ball and stick models) that "proteins are made mostly
of air". Models can be borrowed by educators from their lending library
(http://www.rpc.msoe.edu/cbm/lib/).
Angel Herraez contributes "Biomolecules in the computer: Jmol to the
rescue", introducing Jmol and arguing effectively for the ability of the
Jmol java applet to replace Chime, avoiding many of the problematic issues
with Chime. This is a meaty and scholarly article, amply illustrated, and
including a short glossary.
Finally, I personally enjoyed Howard Dintzis' "The wandering pathway to
determining N to C synthesis of proteins - Some recollections concerning
protein structure and biosynthesis". As a student, he was taught that the
function of DNA is to maintain osmotic balance in the nucleus. His
descriptions of rubbing elbows with Max Perutz, John Kendrew, and Francis
Crick are fascinating, including early searches for mutant human proteins
(culminating in sickle cell hemoglobin). In 1954, they were calculating a
Patterson maps for heavy metal derivitives of myoglobin and hemoglobin on
the vacuum-tube (valve) EDSAC 1, the most powerful digital computer of the
day. Its 1 kilobyte dynamic memory utilized an iron pipe filled with
mercury, in which sound waves traveling between a speaker and a microphone
encoded the data!
-Eric
----
Eric Martz, Professor Emeritus, Dept Microbiology
University of Massachusetts, Amherst MA US
http://www.umass.edu/molvis/martz
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