Basic Information
Gene ID 101689480
Gene Name LEF1
Full Name Uncharacterized protein
Organism Mustela putorius furo [9669]

Cross Reference
UniProt M3YBV7 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMPUP00000008814 Gene3D G3DSA:1.10.30.10 IPR009071 298 380 8.30e-29 High mobility group box domain
ENSMPUP00000008814 Gene3D G3DSA:4.10.900.10 IPR027397 1 70 8.40e-26 Catenin binding domain
ENSMPUP00000008814 PANTHER PTHR10373 IPR024940 1 400 0.00e-00 Transcription factor TCF/LEF
ENSMPUP00000008814 PANTHER PTHR10373:SF11 IPR028769 1 400 0.00e-00 Lymphoid enhancer-binding factor 1
ENSMPUP00000008814 Pfam PF00505 IPR009071 300 367 1.30e-21 High mobility group box domain
ENSMPUP00000008814 Pfam PF08347 IPR013558 1 214 5.70e-74 CTNNB1 binding, N-teminal
ENSMPUP00000008814 ProSiteProfiles PS50118 IPR009071 300 368 0.00e-00 High mobility group box domain
ENSMPUP00000008814 SMART SM00398 IPR009071 299 369 2.50e-25 High mobility group box domain
ENSMPUP00000008814 SUPERFAMILY SSF47095 IPR009071 299 380 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMPUP00000008814 PF08347 0 CTNNB1_binding N-terminal CTNNB1 binding
ENSMPUP00000008814 PF00505 4.7e-22 HMG_box HMG (high mobility group) box
ENSMPUP00000008814 PF09011 7.5e-08 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMPUP00000008814 GO:0006351 biological_process transcription, DNA-templated
ENSMPUP00000008814 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSMPUP00000008814 GO:0060070 biological_process canonical Wnt signaling pathway
ENSMPUP00000008814 GO:0005634 cellular_component nucleus
ENSMPUP00000008814 GO:0005667 cellular_component transcription factor complex
ENSMPUP00000008814 GO:0003677 molecular_function DNA binding
ENSMPUP00000008814 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMPUP00000008814 GO:0008013 molecular_function beta-catenin binding
ENSMPUP00000008814 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9597 Pan paniscus 100995847 13616 Monodelphis domestica 100011783
9986 Oryctolagus cuniculus 100352691 9646 Ailuropoda melanoleuca 100465982
28377 Anolis carolinensis 100556215 9785 Loxodonta africana 100658960
8128 Oreochromis niloticus 100704365 9555 Papio anubis 101017352
39432 Saimiri boliviensis 101047688 9595 Gorilla gorilla 101140253
8090 Oryzias latipes 101167344 13735 Pelodiscus sinensis 102456780
10116 Rattus norvegicus 161452 9358 Choloepus hoffmanni ENSCHOG00000005968
7719 Ciona intestinalis ENSCING00000002003 10141 Cavia porcellus ENSCPOG00000013758
9361 Dasypus novemcinctus ENSDNOG00000019529 10020 Dipodomys ordii ENSDORG00000007694
9796 Equus caballus ENSECAG00000019975 9371 Echinops telfairi ENSETEG00000018357
9685 Felis catus ENSFCAG00000027039 69293 Gasterosteus aculeatus ENSGACG00000017458
8049 Gadus morhua ENSGMOG00000017345 7897 Latimeria chalumnae ENSLACG00000004977
9315 Macropus eugenii ENSMEUG00000006871 9103 Meleagris gallopavo ENSMGAG00000005753
30608 Microcebus murinus ENSMICG00000012833 59463 Myotis lucifugus ENSMLUG00000008891
61853 Nomascus leucogenys ENSNLEG00000012942 9258 Ornithorhynchus anatinus ENSOANG00000002638
9978 Ochotona princeps ENSOPRG00000002250 9813 Procavia capensis ENSPCAG00000012331
132908 Pteropus vampyrus ENSPVAG00000016128 42254 Sorex araneus ENSSARG00000012174
9305 Sarcophilus harrisii ENSSHAG00000003436 43179 Ictidomys tridecemlineatus ENSSTOG00000001371
37347 Tupaia belangeri ENSTBEG00000011345 99883 Tetraodon nigroviridis ENSTNIG00000018022
31033 Takifugu rubripes ENSTRUG00000008652 9478 Tarsius syrichta ENSTSYG00000003979
9739 Tursiops truncatus ENSTTRG00000008109 30538 Vicugna pacos ENSVPAG00000005950
8364 Xenopus tropicalis ENSXETG00000021102 8083 Xiphophorus maculatus ENSXMAG00000010205
7955 Danio rerio 30701 9598 Pan troglodytes 461425
59729 Taeniopygia guttata ENSTGUG00000004013

Paralogs
ENSMPUG00000002032