Basic Information
Gene ID 1390 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name CREM
Full Name cAMP-responsive element modulator
Organism Homo sapiens [9606]

Cross Reference
UniProt Q03060 UniGene Hs.200250
PDB NULL OMIM 123812
KEGG hsa:1390 UCSC uc031pty.1

Protein Interactions
DIP NULL
IntAct Q03060
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000379232 Pfam PF00170 IPR004827 300 356 5.40e-20 Basic-leucine zipper domain
ENSP00000379232 Pfam PF02173 IPR003102 118 156 2.10e-18 Coactivator CBP, pKID
ENSP00000379232 PRINTS PR00041 IPR001630 121 143 5.00e-59 cAMP response element binding (CREB) protein
ENSP00000379232 PRINTS PR00041 IPR001630 170 185 5.00e-59 cAMP response element binding (CREB) protein
ENSP00000379232 PRINTS PR00041 IPR001630 261 272 5.00e-59 cAMP response element binding (CREB) protein
ENSP00000379232 PRINTS PR00041 IPR001630 299 315 5.00e-59 cAMP response element binding (CREB) protein
ENSP00000379232 PRINTS PR00041 IPR001630 317 337 5.00e-59 cAMP response element binding (CREB) protein
ENSP00000379232 PRINTS PR00041 IPR001630 337 354 5.00e-59 cAMP response element binding (CREB) protein
ENSP00000379232 ProSitePatterns PS00036 IPR004827 308 322 - Basic-leucine zipper domain
ENSP00000379232 ProSiteProfiles PS50217 IPR004827 302 353 0.00e-00 Basic-leucine zipper domain
ENSP00000379232 ProSiteProfiles PS50953 IPR003102 104 163 0.00e-00 Coactivator CBP, pKID
ENSP00000379232 SMART SM00338 IPR004827 300 357 9.00e-10 Basic-leucine zipper domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000379232 PF00170 2.7e-20 bZIP_1 bZIP transcription factor
ENSP00000379232 PF02173 8.5e-19 pKID pKID domain
ENSP00000379232 PF07716 3e-07 bZIP_2 Basic region leucine zipper

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000379232 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSP00000379232 GO:0005634 cellular_component nucleus
ENSP00000379232 GO:0005667 cellular_component transcription factor complex
ENSP00000379232 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
6087 Hydra magnipapillata 100200223 9601 Pongo abelii 100433182
9823 Sus scrofa 100512363 61853 Nomascus leucogenys 100586647
10029 Cricetulus griseus 100767867 9597 Pan paniscus 100988448
39432 Saimiri boliviensis 101037962 7897 Latimeria chalumnae 102356299
7668 Strongylocentrotus purpuratus 100889197 9555 Papio anubis 101010751
8083 Xiphophorus maculatus 102221737 13735 Pelodiscus sinensis 102447026
10090 Mus musculus 12916 9615 Canis familiaris 403887
28377 Anolis carolinensis ENSACAG00000000947 9358 Choloepus hoffmanni ENSCHOG00000006471
9483 Callithrix jacchus ENSCJAG00000014066 10141 Cavia porcellus ENSCPOG00000015442
9365 Erinaceus europaeus ENSEEUG00000003158 9685 Felis catus ENSFCAG00000006017
69293 Gasterosteus aculeatus ENSGACG00000014712 9785 Loxodonta africana ENSLAFG00000000007
9315 Macropus eugenii ENSMEUG00000005351 30608 Microcebus murinus ENSMICG00000000835
13616 Monodelphis domestica ENSMODG00000015970 7757 Petromyzon marinus ENSPMAG00000005844
9031 Gallus gallus 395099 7955 Danio rerio 573207
9544 Macaca mulatta 698636 9646 Ailuropoda melanoleuca ENSAMEG00000007902
9913 Bos taurus ENSBTAG00000005474 51511 Ciona savignyi ENSCSAVG00000005696
9361 Dasypus novemcinctus ENSDNOG00000000427 10020 Dipodomys ordii ENSDORG00000001162
9796 Equus caballus ENSECAG00000011220 9371 Echinops telfairi ENSETEG00000004357
9595 Gorilla gorilla ENSGGOG00000003999 9103 Meleagris gallopavo ENSMGAG00000005858
59463 Myotis lucifugus ENSMLUG00000015031 9669 Mustela putorius furo ENSMPUG00000005982
9258 Ornithorhynchus anatinus ENSOANG00000006077 9986 Oryctolagus cuniculus ENSOCUG00000001657
30611 Otolemur garnettii ENSOGAG00000013986 8128 Oreochromis niloticus ENSONIG00000013380
9978 Ochotona princeps ENSOPRG00000002385 8090 Oryzias latipes ENSORLG00000002359
9813 Procavia capensis ENSPCAG00000010193 132908 Pteropus vampyrus ENSPVAG00000005072
9305 Sarcophilus harrisii ENSSHAG00000017148 43179 Ictidomys tridecemlineatus ENSSTOG00000005403
37347 Tupaia belangeri ENSTBEG00000004847 59729 Taeniopygia guttata ENSTGUG00000000919
99883 Tetraodon nigroviridis ENSTNIG00000008335 31033 Takifugu rubripes ENSTRUG00000007984
9478 Tarsius syrichta ENSTSYG00000012085 9739 Tursiops truncatus ENSTTRG00000015733
30538 Vicugna pacos ENSVPAG00000007496 8364 Xenopus tropicalis ENSXETG00000016392