Basic Information | |||
Gene ID | 16372 ; ![]() ![]() | ||
Gene Name | Irx2; Irx6, Irxa2 | ||
Full Name | Iroquois-class homeodomain protein IRX-2 | ||
Organism | Mus musculus [10090] |
Cross Reference | |||
UniProt | P81066 | UniGene | Mm.28888 |
PDB | NULL | OMIM | NULL |
KEGG | mmu:16372 | UCSC | uc007rde.1 |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSMUSP00000073976 | Gene3D | G3DSA:1.10.10.60 | IPR009057 | 118 | 188 | 1.40e-25 | Homeodomain-like |
ENSMUSP00000073976 | Pfam | PF05920 | IPR008422 | 133 | 172 | 3.10e-14 | Homeobox KN domain |
ENSMUSP00000073976 | ProSitePatterns | PS00027 | IPR017970 | 151 | 174 | - | Homeobox, conserved site |
ENSMUSP00000073976 | ProSiteProfiles | PS50071 | IPR001356 | 113 | 176 | 0.00e-00 | Homeobox domain |
ENSMUSP00000073976 | SMART | SM00389 | IPR001356 | 115 | 180 | 4.60e-15 | Homeobox domain |
ENSMUSP00000073976 | SMART | SM00548 | IPR003893 | 325 | 342 | 7.70e-08 | Iroquois-class homeodomain protein |
ENSMUSP00000073976 | SUPERFAMILY | SSF46689 | IPR009057 | 117 | 182 | 0.00e-00 | Homeodomain-like |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSMUSP00000073976 | PF05920 | 1.4e-14 | Homeobox_KN | Homeobox KN domain |
ENSMUSP00000073976 | PF00046 | 1.5e-07 | Homeobox | Homeobox domain |
ENSMUSP00000073976 | PF10210 | 0.00036 | MRP-S32 | Mitochondrial 28S ribosomal protein S32 |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSMUSP00000073976 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSMUSP00000073976 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSMUSP00000073976 | GO:0007275 | biological_process | multicellular organismal development |
ENSMUSP00000073976 | GO:0007399 | biological_process | nervous system development |
ENSMUSP00000073976 | GO:0007420 | biological_process | brain development |
ENSMUSP00000073976 | GO:0009953 | biological_process | dorsal/ventral pattern formation |
ENSMUSP00000073976 | GO:0009954 | biological_process | proximal/distal pattern formation |
ENSMUSP00000073976 | GO:0030154 | biological_process | cell differentiation |
ENSMUSP00000073976 | GO:0005634 | cellular_component | nucleus |
ENSMUSP00000073976 | GO:0003677 | molecular_function | DNA binding |
ENSMUSP00000073976 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSMUSP00000073976 | GO:0043565 | molecular_function | sequence-specific DNA binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
13616 | Monodelphis domestica | 100012318 | 8364 | Xenopus tropicalis | 100038201 |
6087 | Hydra magnipapillata | 100211771 | 9601 | Pongo abelii | 100439691 |
61853 | Nomascus leucogenys | 100601838 | 10029 | Cricetulus griseus | 100773873 |
9597 | Pan paniscus | 100989640 | 9555 | Papio anubis | 100998718 |
7897 | Latimeria chalumnae | 102346061 | 13735 | Pelodiscus sinensis | 102451318 |
9606 | Homo sapiens | 153572 | 39432 | Saimiri boliviensis | 101031491 |
10020 | Dipodomys ordii | ENSDORG00000012071 | 9978 | Ochotona princeps | ENSOPRG00000012917 |
9598 | Pan troglodytes | 471446 | 9615 | Canis familiaris | 487276 |
28377 | Anolis carolinensis | ENSACAG00000000694 | 9646 | Ailuropoda melanoleuca | ENSAMEG00000013363 |
9913 | Bos taurus | ENSBTAG00000047499 | 9483 | Callithrix jacchus | ENSCJAG00000008516 |
10141 | Cavia porcellus | ENSCPOG00000000858 | 7955 | Danio rerio | ENSDARG00000001785 |
9361 | Dasypus novemcinctus | ENSDNOG00000002196 | 9796 | Equus caballus | ENSECAG00000015758 |
9365 | Erinaceus europaeus | ENSEEUG00000015645 | 9371 | Echinops telfairi | ENSETEG00000001553 |
9685 | Felis catus | ENSFCAG00000023076 | 69293 | Gasterosteus aculeatus | ENSGACG00000006581 |
9595 | Gorilla gorilla | ENSGGOG00000015712 | 8049 | Gadus morhua | ENSGMOG00000006674 |
9785 | Loxodonta africana | ENSLAFG00000031893 | 9315 | Macropus eugenii | ENSMEUG00000011565 |
30608 | Microcebus murinus | ENSMICG00000013531 | 59463 | Myotis lucifugus | ENSMLUG00000002364 |
9544 | Macaca mulatta | ENSMMUG00000005802 | 9669 | Mustela putorius furo | ENSMPUG00000007647 |
9258 | Ornithorhynchus anatinus | ENSOANG00000001748 | 9986 | Oryctolagus cuniculus | ENSOCUG00000009172 |
30611 | Otolemur garnettii | ENSOGAG00000012910 | 8128 | Oreochromis niloticus | ENSONIG00000007110 |
8090 | Oryzias latipes | ENSORLG00000005150 | 9813 | Procavia capensis | ENSPCAG00000003649 |
7757 | Petromyzon marinus | ENSPMAG00000002391 | 132908 | Pteropus vampyrus | ENSPVAG00000001273 |
10116 | Rattus norvegicus | ENSRNOG00000011180 | 9305 | Sarcophilus harrisii | ENSSHAG00000006589 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000003533 | 37347 | Tupaia belangeri | ENSTBEG00000000729 |
99883 | Tetraodon nigroviridis | ENSTNIG00000007221 | 31033 | Takifugu rubripes | ENSTRUG00000007607 |
9478 | Tarsius syrichta | ENSTSYG00000006383 | 9739 | Tursiops truncatus | ENSTTRG00000006214 |
8083 | Xiphophorus maculatus | ENSXMAG00000013869 |