Basic Information
Gene ID 16372 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Irx2; Irx6, Irxa2
Full Name Iroquois-class homeodomain protein IRX-2
Organism Mus musculus [10090]

Cross Reference
UniProt P81066 UniGene Mm.28888
PDB NULL OMIM NULL
KEGG mmu:16372 UCSC uc007rde.1

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000073976 Gene3D G3DSA:1.10.10.60 IPR009057 118 188 1.40e-25 Homeodomain-like
ENSMUSP00000073976 Pfam PF05920 IPR008422 133 172 3.10e-14 Homeobox KN domain
ENSMUSP00000073976 ProSitePatterns PS00027 IPR017970 151 174 - Homeobox, conserved site
ENSMUSP00000073976 ProSiteProfiles PS50071 IPR001356 113 176 0.00e-00 Homeobox domain
ENSMUSP00000073976 SMART SM00389 IPR001356 115 180 4.60e-15 Homeobox domain
ENSMUSP00000073976 SMART SM00548 IPR003893 325 342 7.70e-08 Iroquois-class homeodomain protein
ENSMUSP00000073976 SUPERFAMILY SSF46689 IPR009057 117 182 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000073976 PF05920 1.4e-14 Homeobox_KN Homeobox KN domain
ENSMUSP00000073976 PF00046 1.5e-07 Homeobox Homeobox domain
ENSMUSP00000073976 PF10210 0.00036 MRP-S32 Mitochondrial 28S ribosomal protein S32

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000073976 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000073976 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMUSP00000073976 GO:0007275 biological_process multicellular organismal development
ENSMUSP00000073976 GO:0007399 biological_process nervous system development
ENSMUSP00000073976 GO:0007420 biological_process brain development
ENSMUSP00000073976 GO:0009953 biological_process dorsal/ventral pattern formation
ENSMUSP00000073976 GO:0009954 biological_process proximal/distal pattern formation
ENSMUSP00000073976 GO:0030154 biological_process cell differentiation
ENSMUSP00000073976 GO:0005634 cellular_component nucleus
ENSMUSP00000073976 GO:0003677 molecular_function DNA binding
ENSMUSP00000073976 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000073976 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100012318 8364 Xenopus tropicalis 100038201
6087 Hydra magnipapillata 100211771 9601 Pongo abelii 100439691
61853 Nomascus leucogenys 100601838 10029 Cricetulus griseus 100773873
9597 Pan paniscus 100989640 9555 Papio anubis 100998718
7897 Latimeria chalumnae 102346061 13735 Pelodiscus sinensis 102451318
9606 Homo sapiens 153572 39432 Saimiri boliviensis 101031491
10020 Dipodomys ordii ENSDORG00000012071 9978 Ochotona princeps ENSOPRG00000012917
9598 Pan troglodytes 471446 9615 Canis familiaris 487276
28377 Anolis carolinensis ENSACAG00000000694 9646 Ailuropoda melanoleuca ENSAMEG00000013363
9913 Bos taurus ENSBTAG00000047499 9483 Callithrix jacchus ENSCJAG00000008516
10141 Cavia porcellus ENSCPOG00000000858 7955 Danio rerio ENSDARG00000001785
9361 Dasypus novemcinctus ENSDNOG00000002196 9796 Equus caballus ENSECAG00000015758
9365 Erinaceus europaeus ENSEEUG00000015645 9371 Echinops telfairi ENSETEG00000001553
9685 Felis catus ENSFCAG00000023076 69293 Gasterosteus aculeatus ENSGACG00000006581
9595 Gorilla gorilla ENSGGOG00000015712 8049 Gadus morhua ENSGMOG00000006674
9785 Loxodonta africana ENSLAFG00000031893 9315 Macropus eugenii ENSMEUG00000011565
30608 Microcebus murinus ENSMICG00000013531 59463 Myotis lucifugus ENSMLUG00000002364
9544 Macaca mulatta ENSMMUG00000005802 9669 Mustela putorius furo ENSMPUG00000007647
9258 Ornithorhynchus anatinus ENSOANG00000001748 9986 Oryctolagus cuniculus ENSOCUG00000009172
30611 Otolemur garnettii ENSOGAG00000012910 8128 Oreochromis niloticus ENSONIG00000007110
8090 Oryzias latipes ENSORLG00000005150 9813 Procavia capensis ENSPCAG00000003649
7757 Petromyzon marinus ENSPMAG00000002391 132908 Pteropus vampyrus ENSPVAG00000001273
10116 Rattus norvegicus ENSRNOG00000011180 9305 Sarcophilus harrisii ENSSHAG00000006589
43179 Ictidomys tridecemlineatus ENSSTOG00000003533 37347 Tupaia belangeri ENSTBEG00000000729
99883 Tetraodon nigroviridis ENSTNIG00000007221 31033 Takifugu rubripes ENSTRUG00000007607
9478 Tarsius syrichta ENSTSYG00000006383 9739 Tursiops truncatus ENSTTRG00000006214
8083 Xiphophorus maculatus ENSXMAG00000013869