Basic Information | |||
Gene ID | 21410 ; ![]() ![]() | ||
Gene Name | Hnf1b; Hnf-1b, Tcf2 | ||
Full Name | Hepatocyte nuclear factor 1-beta | ||
Organism | Mus musculus [10090] |
Cross Reference | |||
UniProt | P27889 | UniGene | Mm.7226 |
PDB | NULL | OMIM | NULL |
KEGG | mmu:21410 | UCSC | uc007kpx.1 |
Protein Interactions | |
DIP | NULL |
IntAct | P27889 |
MINT | MINT-4097641 |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSMUSP00000021016 | Gene3D | G3DSA:1.10.10.60 | IPR009057 | 235 | 310 | 3.60e-38 | Homeodomain-like |
ENSMUSP00000021016 | Gene3D | G3DSA:1.10.260.40 | IPR010982 | 92 | 185 | 8.60e-44 | Lambda repressor-like, DNA-binding domain |
ENSMUSP00000021016 | Pfam | PF00046 | IPR001356 | 232 | 305 | 4.50e-06 | Homeobox domain |
ENSMUSP00000021016 | Pfam | PF04812 | IPR006897 | 314 | 552 | 2.10e-106 | Hepatocyte nuclear factor 1, beta isoform, C-terminal |
ENSMUSP00000021016 | Pfam | PF04814 | IPR006899 | 1 | 182 | 6.40e-83 | Hepatocyte nuclear factor 1, N-terminal |
ENSMUSP00000021016 | ProSiteProfiles | PS50071 | IPR001356 | 229 | 310 | 0.00e-00 | Homeobox domain |
ENSMUSP00000021016 | SMART | SM00389 | IPR001356 | 231 | 314 | 1.10e-10 | Homeobox domain |
ENSMUSP00000021016 | SUPERFAMILY | SSF100957 | IPR023219 | 1 | 32 | 0.00e-00 | Hepatocyte nuclear factor 1, dimerisation domain |
ENSMUSP00000021016 | SUPERFAMILY | SSF46689 | IPR009057 | 223 | 318 | 0.00e-00 | Homeodomain-like |
ENSMUSP00000021016 | SUPERFAMILY | SSF47413 | IPR010982 | 94 | 184 | 0.00e-00 | Lambda repressor-like, DNA-binding domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSMUSP00000021016 | PF04812 | 0 | HNF-1B_C | Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus |
ENSMUSP00000021016 | PF04814 | 0 | HNF-1_N | Hepatocyte nuclear factor 1 (HNF-1), N terminus |
ENSMUSP00000021016 | PF00046 | 1.6e-06 | Homeobox | Homeobox domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSMUSP00000021016 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSMUSP00000021016 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
ENSMUSP00000021016 | GO:0005634 | cellular_component | nucleus |
ENSMUSP00000021016 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSMUSP00000021016 | GO:0043565 | molecular_function | sequence-specific DNA binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
10029 | Cricetulus griseus | 100771619 | 9305 | Sarcophilus harrisii | 100934366 |
9595 | Gorilla gorilla | 101129879 | 43179 | Ictidomys tridecemlineatus | 101969172 |
7897 | Latimeria chalumnae | 102349678 | 9796 | Equus caballus | 100057769 |
9597 | Pan paniscus | 100982758 | 9555 | Papio anubis | 101013182 |
39432 | Saimiri boliviensis | 101030001 | 9669 | Mustela putorius furo | 101678534 |
13735 | Pelodiscus sinensis | 102451872 | 9615 | Canis familiaris | 610402 |
9544 | Macaca mulatta | 714540 | 28377 | Anolis carolinensis | ENSACAG00000006458 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000013125 | 9358 | Choloepus hoffmanni | ENSCHOG00000006010 |
9483 | Callithrix jacchus | ENSCJAG00000015174 | 10141 | Cavia porcellus | ENSCPOG00000001234 |
7955 | Danio rerio | ENSDARG00000022295 | 10020 | Dipodomys ordii | ENSDORG00000009669 |
9371 | Echinops telfairi | ENSETEG00000019192 | 9685 | Felis catus | ENSFCAG00000000241 |
69293 | Gasterosteus aculeatus | ENSGACG00000011101 | 9031 | Gallus gallus | ENSGALG00000005504 |
9785 | Loxodonta africana | ENSLAFG00000002573 | 9103 | Meleagris gallopavo | ENSMGAG00000008126 |
30608 | Microcebus murinus | ENSMICG00000001274 | 59463 | Myotis lucifugus | ENSMLUG00000012260 |
13616 | Monodelphis domestica | ENSMODG00000019108 | 61853 | Nomascus leucogenys | ENSNLEG00000002919 |
30611 | Otolemur garnettii | ENSOGAG00000000869 | 9813 | Procavia capensis | ENSPCAG00000008147 |
7757 | Petromyzon marinus | ENSPMAG00000001209 | 10116 | Rattus norvegicus | ENSRNOG00000002598 |
42254 | Sorex araneus | ENSSARG00000007152 | 9823 | Sus scrofa | ENSSSCG00000022417 |
37347 | Tupaia belangeri | ENSTBEG00000007107 | 59729 | Taeniopygia guttata | ENSTGUG00000008342 |
99883 | Tetraodon nigroviridis | ENSTNIG00000016225 | 31033 | Takifugu rubripes | ENSTRUG00000003809 |
9478 | Tarsius syrichta | ENSTSYG00000010701 | 9739 | Tursiops truncatus | ENSTTRG00000015910 |
8083 | Xiphophorus maculatus | ENSXMAG00000011775 | 8364 | Xenopus tropicalis | 733490 |
9365 | Erinaceus europaeus | ENSEEUG00000004998 | 8049 | Gadus morhua | ENSGMOG00000016065 |
9315 | Macropus eugenii | ENSMEUG00000004443 | 9258 | Ornithorhynchus anatinus | ENSOANG00000007132 |
8128 | Oreochromis niloticus | ENSONIG00000013161 | 9978 | Ochotona princeps | ENSOPRG00000003933 |
8090 | Oryzias latipes | ENSORLG00000004564 | 132908 | Pteropus vampyrus | ENSPVAG00000010466 |
30538 | Vicugna pacos | ENSVPAG00000001980 |