Basic Information
Gene ID 3090 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name HIC1; ZBTB29
Full Name Hypermethylated in cancer 1 protein
Organism Homo sapiens [9606]

Cross Reference
UniProt Q14526 UniGene Hs.72956
PDB NULL OMIM 603825
KEGG hsa:3090 UCSC uc002fty.4

Protein Interactions
DIP NULL
IntAct Q14526
MINT MINT-2730619
STRING 9606.ENSP00000314080

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000314080 Gene3D G3DSA:3.30.160.60 IPR013087 505 536 1.60e-07 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000314080 Gene3D G3DSA:3.30.160.60 IPR013087 537 559 1.10e-12 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000314080 Gene3D G3DSA:3.30.160.60 IPR013087 560 582 5.10e-14 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000314080 Gene3D G3DSA:3.30.160.60 IPR013087 583 613 1.00e-14 Zinc finger C2H2-type/integrase DNA-binding domain
ENSP00000314080 Gene3D G3DSA:3.30.710.10 IPR011333 24 149 1.20e-28 BTB/POZ fold
ENSP00000314080 PANTHER PTHR11389:SF322 IPR028424 1 616 0.00e-00 Hypermethylated in cancer 1 protein
ENSP00000314080 Pfam PF00096 IPR007087 507 529 2.50e-04 Zinc finger, C2H2
ENSP00000314080 Pfam PF00096 IPR007087 535 557 1.70e-05 Zinc finger, C2H2
ENSP00000314080 Pfam PF00651 IPR013069 37 152 9.90e-23 BTB/POZ
ENSP00000314080 ProSitePatterns PS00028 IPR007087 439 459 - Zinc finger, C2H2
ENSP00000314080 ProSitePatterns PS00028 IPR007087 509 529 - Zinc finger, C2H2
ENSP00000314080 ProSitePatterns PS00028 IPR007087 537 557 - Zinc finger, C2H2
ENSP00000314080 ProSitePatterns PS00028 IPR007087 565 585 - Zinc finger, C2H2
ENSP00000314080 ProSitePatterns PS00028 IPR007087 593 613 - Zinc finger, C2H2
ENSP00000314080 ProSiteProfiles PS50097 IPR000210 47 110 0.00e-00 BTB/POZ-like
ENSP00000314080 ProSiteProfiles PS50157 IPR007087 437 464 0.00e-00 Zinc finger, C2H2
ENSP00000314080 ProSiteProfiles PS50157 IPR007087 507 534 0.00e-00 Zinc finger, C2H2
ENSP00000314080 ProSiteProfiles PS50157 IPR007087 535 562 0.00e-00 Zinc finger, C2H2
ENSP00000314080 ProSiteProfiles PS50157 IPR007087 563 590 0.00e-00 Zinc finger, C2H2
ENSP00000314080 ProSiteProfiles PS50157 IPR007087 591 614 0.00e-00 Zinc finger, C2H2
ENSP00000314080 SMART SM00225 IPR000210 47 153 1.20e-25 BTB/POZ-like
ENSP00000314080 SMART SM00355 IPR015880 437 459 3.50e-04 Zinc finger, C2H2-like
ENSP00000314080 SMART SM00355 IPR015880 507 529 3.90e-05 Zinc finger, C2H2-like
ENSP00000314080 SMART SM00355 IPR015880 535 557 3.00e-08 Zinc finger, C2H2-like
ENSP00000314080 SMART SM00355 IPR015880 563 585 1.50e-06 Zinc finger, C2H2-like
ENSP00000314080 SMART SM00355 IPR015880 591 613 1.70e-06 Zinc finger, C2H2-like
ENSP00000314080 SUPERFAMILY SSF54695 IPR011333 24 151 0.00e-00 BTB/POZ fold

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000314080 PF00651 6.5e-23 BTB BTB/POZ domain
ENSP00000314080 PF00096 1.4e-21 zf-C2H2 Zinc finger, C2H2 type
ENSP00000314080 PF13465 2.1e-19 zf-H2C2_2 Zinc-finger double domain
ENSP00000314080 PF12171 1.7e-17 zf-C2H2_jaz Zinc-finger double-stranded RNA-binding
ENSP00000314080 PF13894 1.1e-16 zf-C2H2_4 C2H2-type zinc finger
ENSP00000314080 PF12874 5.8e-10 zf-met Zinc-finger of C2H2 type
ENSP00000314080 PF13912 5.4e-09 zf-C2H2_6 C2H2-type zinc finger
ENSP00000314080 PF12756 8.2e-05 zf-C2H2_2 C2H2 type zinc-finger (2 copies)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000314080 GO:0006351 biological_process transcription, DNA-templated
ENSP00000314080 GO:0005634 cellular_component nucleus
ENSP00000314080 GO:0003677 molecular_function DNA binding
ENSP00000314080 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9823 Sus scrofa 100525779 8128 Oreochromis niloticus 100694398
30611 Otolemur garnettii 100954137 9597 Pan paniscus 100994626
9555 Papio anubis 101021001 39432 Saimiri boliviensis 101041445
9669 Mustela putorius furo 101674299 7897 Latimeria chalumnae 102359906
9913 Bos taurus ENSBTAG00000025130 10141 Cavia porcellus ENSCPOG00000020382
9796 Equus caballus ENSECAG00000004462 69293 Gasterosteus aculeatus ENSGACG00000010848
9595 Gorilla gorilla ENSGGOG00000027584 9785 Loxodonta africana ENSLAFG00000001259
9103 Meleagris gallopavo ENSMGAG00000005397 30608 Microcebus murinus ENSMICG00000012908
9544 Macaca mulatta ENSMMUG00000030393 13616 Monodelphis domestica ENSMODG00000010600
10090 Mus musculus ENSMUSG00000043099 8090 Oryzias latipes ENSORLG00000004895
9813 Procavia capensis ENSPCAG00000000535 9601 Pongo abelii ENSPPYG00000007789
9598 Pan troglodytes ENSPTRG00000008543 132908 Pteropus vampyrus ENSPVAG00000002158
10116 Rattus norvegicus ENSRNOG00000003096 42254 Sorex araneus ENSSARG00000010162
43179 Ictidomys tridecemlineatus ENSSTOG00000011792 59729 Taeniopygia guttata ENSTGUG00000005835
31033 Takifugu rubripes ENSTRUG00000004590 8083 Xiphophorus maculatus ENSXMAG00000001419
9646 Ailuropoda melanoleuca ENSAMEG00000007657 10020 Dipodomys ordii ENSDORG00000016613
9031 Gallus gallus ENSGALG00000026718 59463 Myotis lucifugus ENSMLUG00000010527
13735 Pelodiscus sinensis ENSPSIG00000007902