Basic Information
Gene ID 456149
Gene Name HIF3A
Full Name Uncharacterized protein
Organism Pan troglodytes [9598]

Cross Reference
UniProt H2R5Y9 UniGene NULL
PDB NULL OMIM NULL
KEGG ptr:456149 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPTRP00000048600 Pfam PF00989 IPR013767 90 144 9.60e-07 PAS fold
ENSPTRP00000048600 Pfam PF11413 IPR021537 476 507 5.40e-15 Hypoxia-inducible factor, alpha subunit
ENSPTRP00000048600 ProSiteProfiles PS50112 IPR000014 244 295 0.00e-00 PAS domain
ENSPTRP00000048600 ProSiteProfiles PS50112 IPR000014 88 152 0.00e-00 PAS domain
ENSPTRP00000048600 ProSiteProfiles PS50888 IPR011598 12 65 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPTRP00000048600 SMART SM00086 IPR001610 299 342 1.20e-04 PAC motif
ENSPTRP00000048600 SMART SM00091 IPR000014 225 293 2.80e-05 PAS domain
ENSPTRP00000048600 SMART SM00091 IPR000014 82 148 1.10e-12 PAS domain
ENSPTRP00000048600 SMART SM00353 IPR011598 18 73 5.40e-10 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPTRP00000048600 SUPERFAMILY SSF47459 IPR011598 12 68 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSPTRP00000048600 SUPERFAMILY SSF55785 IPR000014 239 339 0.00e-00 PAS domain
ENSPTRP00000048600 SUPERFAMILY SSF55785 IPR000014 91 153 0.00e-00 PAS domain
ENSPTRP00000048600 TIGRFAM TIGR00229 IPR000014 246 322 5.90e-06 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPTRP00000048600 PF14598 3e-22 PAS_11 PAS domain
ENSPTRP00000048600 PF08447 7.7e-21 PAS_3 PAS fold
ENSPTRP00000048600 PF00989 1.8e-15 PAS PAS fold
ENSPTRP00000048600 PF11413 2.6e-15 HIF-1 Hypoxia-inducible factor-1
ENSPTRP00000048600 PF13426 2.8e-09 PAS_9 PAS domain
ENSPTRP00000048600 PF08448 8.2e-08 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPTRP00000048600 GO:0001666 biological_process response to hypoxia
ENSPTRP00000048600 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSPTRP00000048600 GO:0071456 biological_process cellular response to hypoxia
ENSPTRP00000048600 GO:0005634 cellular_component nucleus
ENSPTRP00000048600 GO:0005737 cellular_component cytoplasm
ENSPTRP00000048600 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPTRP00000048600 GO:0004871 molecular_function signal transducer activity
ENSPTRP00000048600 GO:0035035 molecular_function histone acetyltransferase binding
ENSPTRP00000048600 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
61853 Nomascus leucogenys 100582446 9597 Pan paniscus 100979253
9555 Papio anubis 101007659 39432 Saimiri boliviensis 101027930
9595 Gorilla gorilla 101146641 43179 Ictidomys tridecemlineatus 101976940
10090 Mus musculus 53417 9606 Homo sapiens 64344
28377 Anolis carolinensis ENSACAG00000016766 9646 Ailuropoda melanoleuca ENSAMEG00000008615
10141 Cavia porcellus ENSCPOG00000024199 10020 Dipodomys ordii ENSDORG00000004664
9796 Equus caballus ENSECAG00000020693 9365 Erinaceus europaeus ENSEEUG00000009703
9685 Felis catus ENSFCAG00000014181 9315 Macropus eugenii ENSMEUG00000002474
30608 Microcebus murinus ENSMICG00000016033 59463 Myotis lucifugus ENSMLUG00000014423
9669 Mustela putorius furo ENSMPUG00000005285 30611 Otolemur garnettii ENSOGAG00000008187
9978 Ochotona princeps ENSOPRG00000014480 9813 Procavia capensis ENSPCAG00000006067
9601 Pongo abelii ENSPPYG00000010147 132908 Pteropus vampyrus ENSPVAG00000003553
10116 Rattus norvegicus ENSRNOG00000017198 9305 Sarcophilus harrisii ENSSHAG00000004128
9823 Sus scrofa ENSSSCG00000003101 37347 Tupaia belangeri ENSTBEG00000002129
9478 Tarsius syrichta ENSTSYG00000009179 8083 Xiphophorus maculatus ENSXMAG00000003186
9785 Loxodonta africana ENSLAFG00000017230 9739 Tursiops truncatus ENSTTRG00000001609