Basic Information
Gene ID 468537
Gene Name SMAD4
Full Name SMAD family member 4
Organism Pan troglodytes [9598]

Cross Reference
UniProt H2QEJ6 UniGene NULL
PDB NULL OMIM NULL
KEGG ptr:468537 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPTRP00000017047 Gene3D G3DSA:2.60.200.10 IPR017855 315 548 5.50e-121 SMAD domain-like
ENSPTRP00000017047 Gene3D G3DSA:3.90.520.10 IPR013019 12 141 1.20e-51 MAD homology, MH1
ENSPTRP00000017047 PANTHER PTHR13703 IPR013790 1 552 0.00e-00 Dwarfin
ENSPTRP00000017047 Pfam PF03165 IPR003619 37 137 7.60e-40 MAD homology 1, Dwarfin-type
ENSPTRP00000017047 Pfam PF03166 IPR001132 319 531 5.00e-77 SMAD domain, Dwarfin-type
ENSPTRP00000017047 ProSiteProfiles PS51075 IPR013019 18 142 0.00e-00 MAD homology, MH1
ENSPTRP00000017047 ProSiteProfiles PS51076 IPR001132 323 552 0.00e-00 SMAD domain, Dwarfin-type
ENSPTRP00000017047 SMART SM00523 IPR003619 31 140 1.20e-67 MAD homology 1, Dwarfin-type
ENSPTRP00000017047 SMART SM00524 IPR001132 321 530 4.00e-126 SMAD domain, Dwarfin-type
ENSPTRP00000017047 SUPERFAMILY SSF49879 IPR008984 287 544 0.00e-00 SMAD/FHA domain
ENSPTRP00000017047 SUPERFAMILY SSF56366 IPR013019 19 137 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPTRP00000017047 PF03166 0 MH2 MH2 domain
ENSPTRP00000017047 PF03165 3.60001e-40 MH1 MH1 domain
ENSPTRP00000017047 PF10401 0.00055 IRF-3 Interferon-regulatory factor 3

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPTRP00000017047 GO:0006351 biological_process transcription, DNA-templated
ENSPTRP00000017047 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSPTRP00000017047 GO:0005667 cellular_component transcription factor complex
ENSPTRP00000017047 GO:0005737 cellular_component cytoplasm
ENSPTRP00000017047 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPTRP00000017047 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7029 Acyrthosiphon pisum 100158948 6087 Hydra magnipapillata 100198878
10224 Saccoglossus kowalevskii 100369846 9483 Callithrix jacchus 100409302
28377 Anolis carolinensis 100552093 400682 Amphimedon queenslandica 100637596
30195 Bombus terrestris 100644192 7425 Nasonia vitripennis 100677849
8128 Oreochromis niloticus 100708381 132113 Bombus impatiens 100745462
7463 Apis florea 100869046 34638 Metaseiulus occidentalis 100903134
9597 Pan paniscus 100991127 9555 Papio anubis 101019266
39432 Saimiri boliviensis 101032066 9685 Felis catus 101093650
9595 Gorilla gorilla 101153595 9669 Mustela putorius furo 101675099
8083 Xiphophorus maculatus 102228719 7897 Latimeria chalumnae 102358988
13735 Pelodiscus sinensis 102451711 10090 Mus musculus 17128
7460 Apis mellifera 409321 7227 Drosophila melanogaster 43725
9796 Equus caballus 100033846 9785 Loxodonta africana 100659509
143995 Megachile rotundata 100879968 7955 Danio rerio 560317
7668 Strongylocentrotus purpuratus 575230 7070 Tribolium castaneum 660074
9544 Macaca mulatta 701803 7719 Ciona intestinalis 778905
9358 Choloepus hoffmanni ENSCHOG00000000860 10141 Cavia porcellus ENSCPOG00000006470
51511 Ciona savignyi ENSCSAVG00000006480 9361 Dasypus novemcinctus ENSDNOG00000005063
10020 Dipodomys ordii ENSDORG00000009089 9365 Erinaceus europaeus ENSEEUG00000001575
9371 Echinops telfairi ENSETEG00000007750 69293 Gasterosteus aculeatus ENSGACG00000007495
8049 Gadus morhua ENSGMOG00000005844 9315 Macropus eugenii ENSMEUG00000001823
30608 Microcebus murinus ENSMICG00000017525 59463 Myotis lucifugus ENSMLUG00000013944
13616 Monodelphis domestica ENSMODG00000010995 9258 Ornithorhynchus anatinus ENSOANG00000008117
9978 Ochotona princeps ENSOPRG00000013601 8090 Oryzias latipes ENSORLG00000007703
9813 Procavia capensis ENSPCAG00000009142 7757 Petromyzon marinus ENSPMAG00000009414
132908 Pteropus vampyrus ENSPVAG00000004261 10116 Rattus norvegicus ENSRNOG00000015634
42254 Sorex araneus ENSSARG00000013883 9305 Sarcophilus harrisii ENSSHAG00000010344
43179 Ictidomys tridecemlineatus ENSSTOG00000028580 37347 Tupaia belangeri ENSTBEG00000014105
99883 Tetraodon nigroviridis ENSTNIG00000003193 31033 Takifugu rubripes ENSTRUG00000014045
9478 Tarsius syrichta ENSTSYG00000009792 9739 Tursiops truncatus ENSTTRG00000011767
30538 Vicugna pacos ENSVPAG00000006757 8364 Xenopus tropicalis ENSXETG00000022355