Basic Information
Gene ID 5077 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name PAX3; HUP2
Full Name Paired box protein Pax-3
Organism Homo sapiens [9606]

Cross Reference
UniProt P23760 UniGene Hs.42146
PDB 3CMY OMIM 606597
KEGG hsa:5077 UCSC uc010fwo.3

Protein Interactions
DIP NULL
IntAct P23760
MINT MINT-202884
STRING 9606.ENSP00000375921

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000375921 Gene3D G3DSA:1.10.10.10 IPR011991 103 166 3.60e-34 Winged helix-turn-helix DNA-binding domain
ENSP00000375921 Gene3D G3DSA:1.10.10.10 IPR011991 37 102 6.20e-41 Winged helix-turn-helix DNA-binding domain
ENSP00000375921 Gene3D G3DSA:1.10.10.60 IPR009057 221 281 5.90e-30 Homeodomain-like
ENSP00000375921 Pfam PF00046 IPR001356 220 276 1.20e-22 Homeobox domain
ENSP00000375921 Pfam PF00292 IPR001523 34 159 1.10e-74 Paired domain
ENSP00000375921 Pfam PF12360 IPR022106 346 391 1.10e-23 Paired box protein 7
ENSP00000375921 PRINTS PR00027 IPR001523 38 53 1.30e-38 Paired domain
ENSP00000375921 PRINTS PR00027 IPR001523 56 74 1.30e-38 Paired domain
ENSP00000375921 PRINTS PR00027 IPR001523 76 93 1.30e-38 Paired domain
ENSP00000375921 PRINTS PR00027 IPR001523 94 111 1.30e-38 Paired domain
ENSP00000375921 ProSitePatterns PS00027 IPR017970 252 275 - Homeobox, conserved site
ENSP00000375921 ProSitePatterns PS00034 IPR001523 68 84 - Paired domain
ENSP00000375921 ProSiteProfiles PS50071 IPR001356 217 277 0.00e-00 Homeobox domain
ENSP00000375921 ProSiteProfiles PS51057 IPR001523 34 161 0.00e-00 Paired domain
ENSP00000375921 SMART SM00351 IPR001523 34 159 6.80e-94 Paired domain
ENSP00000375921 SMART SM00389 IPR001356 219 281 2.60e-29 Homeobox domain
ENSP00000375921 SUPERFAMILY SSF46689 IPR009057 212 285 0.00e-00 Homeodomain-like
ENSP00000375921 SUPERFAMILY SSF46689 IPR009057 36 159 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000375921 PF00292 0 PAX 'Paired box' domain
ENSP00000375921 PF12360 4.8e-24 Pax7 Paired box protein 7
ENSP00000375921 PF00046 6.4e-23 Homeobox Homeobox domain
ENSP00000375921 PF13551 9.4e-06 HTH_29 Winged helix-turn helix
ENSP00000375921 PF13384 9.6e-06 HTH_23 Homeodomain-like domain
ENSP00000375921 PF13565 2.7e-05 HTH_32 Homeodomain-like domain
ENSP00000375921 PF05920 0.00028 Homeobox_KN Homeobox KN domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000375921 GO:0005634 cellular_component nucleus
ENSP00000375921 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000375921 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100114080 7029 Acyrthosiphon pisum 100163852
28377 Anolis carolinensis 100560571 30195 Bombus terrestris 100650218
8128 Oreochromis niloticus 100698441 10029 Cricetulus griseus 100762293
7463 Apis florea 100868259 143995 Megachile rotundata 100880900
9597 Pan paniscus 100975447 39432 Saimiri boliviensis 101042763
8083 Xiphophorus maculatus 102221927 13735 Pelodiscus sinensis 102448040
6239 Caenorhabditis elegans 185022 10116 Rattus norvegicus 500574
9986 Oryctolagus cuniculus 100357318 132113 Bombus impatiens 100746231
34638 Metaseiulus occidentalis 100899677 9555 Papio anubis 101016355
9669 Mustela putorius furo 101693051 43179 Ictidomys tridecemlineatus 101976642
10090 Mus musculus 18509 7227 Drosophila melanogaster 34629
9913 Bos taurus 540951 7070 Tribolium castaneum 663057
9646 Ailuropoda melanoleuca ENSAMEG00000007444 9365 Erinaceus europaeus ENSEEUG00000012346
69293 Gasterosteus aculeatus ENSGACG00000014017 9315 Macropus eugenii ENSMEUG00000013628
30608 Microcebus murinus ENSMICG00000000336 30611 Otolemur garnettii ENSOGAG00000001304
8090 Oryzias latipes ENSORLG00000009031 42254 Sorex araneus ENSSARG00000008062
9305 Sarcophilus harrisii ENSSHAG00000016542 59729 Taeniopygia guttata ENSTGUG00000007761
9478 Tarsius syrichta ENSTSYG00000009638 9615 Canis familiaris ENSCAFG00000016041
9358 Choloepus hoffmanni ENSCHOG00000005130 7719 Ciona intestinalis ENSCING00000005904
9483 Callithrix jacchus ENSCJAG00000012088 10141 Cavia porcellus ENSCPOG00000006276
51511 Ciona savignyi ENSCSAVG00000004794 7955 Danio rerio ENSDARG00000028348
9361 Dasypus novemcinctus ENSDNOG00000001871 10020 Dipodomys ordii ENSDORG00000010324
9796 Equus caballus ENSECAG00000020207 9371 Echinops telfairi ENSETEG00000006800
9685 Felis catus ENSFCAG00000018967 9031 Gallus gallus ENSGALG00000005246
9595 Gorilla gorilla ENSGGOG00000015636 8049 Gadus morhua ENSGMOG00000001549
7897 Latimeria chalumnae ENSLACG00000006342 9785 Loxodonta africana ENSLAFG00000008041
9103 Meleagris gallopavo ENSMGAG00000005870 59463 Myotis lucifugus ENSMLUG00000014155
9544 Macaca mulatta ENSMMUG00000017444 61853 Nomascus leucogenys ENSNLEG00000009611
9258 Ornithorhynchus anatinus ENSOANG00000007096 9978 Ochotona princeps ENSOPRG00000004223
9813 Procavia capensis ENSPCAG00000000403 7757 Petromyzon marinus ENSPMAG00000010414
9598 Pan troglodytes ENSPTRG00000012969 132908 Pteropus vampyrus ENSPVAG00000007498
9823 Sus scrofa ENSSSCG00000028418 37347 Tupaia belangeri ENSTBEG00000010268
99883 Tetraodon nigroviridis ENSTNIG00000014313 31033 Takifugu rubripes ENSTRUG00000009198
9739 Tursiops truncatus ENSTTRG00000000379 30538 Vicugna pacos ENSVPAG00000000715
8364 Xenopus tropicalis ENSXETG00000007640