Basic Information | |||
Gene ID | 5077 ; ![]() ![]() | ||
Gene Name | PAX3; HUP2 | ||
Full Name | Paired box protein Pax-3 | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P23760 | UniGene | Hs.42146 |
PDB | 3CMY | OMIM | 606597 |
KEGG | hsa:5077 | UCSC | uc010fwo.3 |
Protein Interactions | |
DIP | NULL |
IntAct | P23760 |
MINT | MINT-202884 |
STRING | 9606.ENSP00000375921 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000375921 | Gene3D | G3DSA:1.10.10.10 | IPR011991 | 103 | 166 | 3.60e-34 | Winged helix-turn-helix DNA-binding domain |
ENSP00000375921 | Gene3D | G3DSA:1.10.10.10 | IPR011991 | 37 | 102 | 6.20e-41 | Winged helix-turn-helix DNA-binding domain |
ENSP00000375921 | Gene3D | G3DSA:1.10.10.60 | IPR009057 | 221 | 281 | 5.90e-30 | Homeodomain-like |
ENSP00000375921 | Pfam | PF00046 | IPR001356 | 220 | 276 | 1.20e-22 | Homeobox domain |
ENSP00000375921 | Pfam | PF00292 | IPR001523 | 34 | 159 | 1.10e-74 | Paired domain |
ENSP00000375921 | Pfam | PF12360 | IPR022106 | 346 | 391 | 1.10e-23 | Paired box protein 7 |
ENSP00000375921 | PRINTS | PR00027 | IPR001523 | 38 | 53 | 1.30e-38 | Paired domain |
ENSP00000375921 | PRINTS | PR00027 | IPR001523 | 56 | 74 | 1.30e-38 | Paired domain |
ENSP00000375921 | PRINTS | PR00027 | IPR001523 | 76 | 93 | 1.30e-38 | Paired domain |
ENSP00000375921 | PRINTS | PR00027 | IPR001523 | 94 | 111 | 1.30e-38 | Paired domain |
ENSP00000375921 | ProSitePatterns | PS00027 | IPR017970 | 252 | 275 | - | Homeobox, conserved site |
ENSP00000375921 | ProSitePatterns | PS00034 | IPR001523 | 68 | 84 | - | Paired domain |
ENSP00000375921 | ProSiteProfiles | PS50071 | IPR001356 | 217 | 277 | 0.00e-00 | Homeobox domain |
ENSP00000375921 | ProSiteProfiles | PS51057 | IPR001523 | 34 | 161 | 0.00e-00 | Paired domain |
ENSP00000375921 | SMART | SM00351 | IPR001523 | 34 | 159 | 6.80e-94 | Paired domain |
ENSP00000375921 | SMART | SM00389 | IPR001356 | 219 | 281 | 2.60e-29 | Homeobox domain |
ENSP00000375921 | SUPERFAMILY | SSF46689 | IPR009057 | 212 | 285 | 0.00e-00 | Homeodomain-like |
ENSP00000375921 | SUPERFAMILY | SSF46689 | IPR009057 | 36 | 159 | 0.00e-00 | Homeodomain-like |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000375921 | PF00292 | 0 | PAX | 'Paired box' domain |
ENSP00000375921 | PF12360 | 4.8e-24 | Pax7 | Paired box protein 7 |
ENSP00000375921 | PF00046 | 6.4e-23 | Homeobox | Homeobox domain |
ENSP00000375921 | PF13551 | 9.4e-06 | HTH_29 | Winged helix-turn helix |
ENSP00000375921 | PF13384 | 9.6e-06 | HTH_23 | Homeodomain-like domain |
ENSP00000375921 | PF13565 | 2.7e-05 | HTH_32 | Homeodomain-like domain |
ENSP00000375921 | PF05920 | 0.00028 | Homeobox_KN | Homeobox KN domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSP00000375921 | GO:0005634 | cellular_component | nucleus |
ENSP00000375921 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSP00000375921 | GO:0043565 | molecular_function | sequence-specific DNA binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
7425 | Nasonia vitripennis | 100114080 | 7029 | Acyrthosiphon pisum | 100163852 |
28377 | Anolis carolinensis | 100560571 | 30195 | Bombus terrestris | 100650218 |
8128 | Oreochromis niloticus | 100698441 | 10029 | Cricetulus griseus | 100762293 |
7463 | Apis florea | 100868259 | 143995 | Megachile rotundata | 100880900 |
9597 | Pan paniscus | 100975447 | 39432 | Saimiri boliviensis | 101042763 |
8083 | Xiphophorus maculatus | 102221927 | 13735 | Pelodiscus sinensis | 102448040 |
6239 | Caenorhabditis elegans | 185022 | 10116 | Rattus norvegicus | 500574 |
9986 | Oryctolagus cuniculus | 100357318 | 132113 | Bombus impatiens | 100746231 |
34638 | Metaseiulus occidentalis | 100899677 | 9555 | Papio anubis | 101016355 |
9669 | Mustela putorius furo | 101693051 | 43179 | Ictidomys tridecemlineatus | 101976642 |
10090 | Mus musculus | 18509 | 7227 | Drosophila melanogaster | 34629 |
9913 | Bos taurus | 540951 | 7070 | Tribolium castaneum | 663057 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000007444 | 9365 | Erinaceus europaeus | ENSEEUG00000012346 |
69293 | Gasterosteus aculeatus | ENSGACG00000014017 | 9315 | Macropus eugenii | ENSMEUG00000013628 |
30608 | Microcebus murinus | ENSMICG00000000336 | 30611 | Otolemur garnettii | ENSOGAG00000001304 |
8090 | Oryzias latipes | ENSORLG00000009031 | 42254 | Sorex araneus | ENSSARG00000008062 |
9305 | Sarcophilus harrisii | ENSSHAG00000016542 | 59729 | Taeniopygia guttata | ENSTGUG00000007761 |
9478 | Tarsius syrichta | ENSTSYG00000009638 | 9615 | Canis familiaris | ENSCAFG00000016041 |
9358 | Choloepus hoffmanni | ENSCHOG00000005130 | 7719 | Ciona intestinalis | ENSCING00000005904 |
9483 | Callithrix jacchus | ENSCJAG00000012088 | 10141 | Cavia porcellus | ENSCPOG00000006276 |
51511 | Ciona savignyi | ENSCSAVG00000004794 | 7955 | Danio rerio | ENSDARG00000028348 |
9361 | Dasypus novemcinctus | ENSDNOG00000001871 | 10020 | Dipodomys ordii | ENSDORG00000010324 |
9796 | Equus caballus | ENSECAG00000020207 | 9371 | Echinops telfairi | ENSETEG00000006800 |
9685 | Felis catus | ENSFCAG00000018967 | 9031 | Gallus gallus | ENSGALG00000005246 |
9595 | Gorilla gorilla | ENSGGOG00000015636 | 8049 | Gadus morhua | ENSGMOG00000001549 |
7897 | Latimeria chalumnae | ENSLACG00000006342 | 9785 | Loxodonta africana | ENSLAFG00000008041 |
9103 | Meleagris gallopavo | ENSMGAG00000005870 | 59463 | Myotis lucifugus | ENSMLUG00000014155 |
9544 | Macaca mulatta | ENSMMUG00000017444 | 61853 | Nomascus leucogenys | ENSNLEG00000009611 |
9258 | Ornithorhynchus anatinus | ENSOANG00000007096 | 9978 | Ochotona princeps | ENSOPRG00000004223 |
9813 | Procavia capensis | ENSPCAG00000000403 | 7757 | Petromyzon marinus | ENSPMAG00000010414 |
9598 | Pan troglodytes | ENSPTRG00000012969 | 132908 | Pteropus vampyrus | ENSPVAG00000007498 |
9823 | Sus scrofa | ENSSSCG00000028418 | 37347 | Tupaia belangeri | ENSTBEG00000010268 |
99883 | Tetraodon nigroviridis | ENSTNIG00000014313 | 31033 | Takifugu rubripes | ENSTRUG00000009198 |
9739 | Tursiops truncatus | ENSTTRG00000000379 | 30538 | Vicugna pacos | ENSVPAG00000000715 |
8364 | Xenopus tropicalis | ENSXETG00000007640 |