Basic Information
Gene ID 534935
Gene Name TCF7L2; TCF4
Full Name TCF7L2 protein
Organism Bos taurus [9913]

Cross Reference
UniProt A6QPK5 UniGene Bt.91190
PDB NULL OMIM NULL
KEGG bta:534935 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9913.ENSBTAP00000030974

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSBTAP00000030974 Gene3D G3DSA:4.10.280.10 IPR011598 545 604 2.90e-27 Myc-type, basic helix-loop-helix (bHLH) domain
ENSBTAP00000030974 Pfam PF00010 IPR011598 545 598 2.50e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSBTAP00000030974 ProSiteProfiles PS50888 IPR011598 544 597 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSBTAP00000030974 SMART SM00353 IPR011598 550 603 1.20e-13 Myc-type, basic helix-loop-helix (bHLH) domain
ENSBTAP00000030974 SUPERFAMILY SSF47459 IPR011598 536 603 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSBTAP00000030974 PF00010 1.2e-11 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSBTAP00000030974 GO:0006351 biological_process transcription, DNA-templated
ENSBTAP00000030974 GO:0045666 biological_process positive regulation of neuron differentiation
ENSBTAP00000030974 GO:0005634 cellular_component nucleus
ENSBTAP00000030974 GO:0046982 molecular_function protein heterodimerization activity
ENSBTAP00000030974 GO:0070888 molecular_function E-box binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100396827 8128 Oreochromis niloticus 100694308
7463 Apis florea 100867106 9597 Pan paniscus 100967508
9555 Papio anubis 100998264 39432 Saimiri boliviensis 101053606
9685 Felis catus 101097354 7668 Strongylocentrotus purpuratus 581618
9615 Canis familiaris ENSCAFG00000000140 9358 Choloepus hoffmanni ENSCHOG00000000331
9361 Dasypus novemcinctus ENSDNOG00000013859 10020 Dipodomys ordii ENSDORG00000012697
9796 Equus caballus ENSECAG00000017265 9365 Erinaceus europaeus ENSEEUG00000000134
9371 Echinops telfairi ENSETEG00000001948 9595 Gorilla gorilla ENSGGOG00000016297
8049 Gadus morhua ENSGMOG00000018104 7897 Latimeria chalumnae ENSLACG00000003485
9315 Macropus eugenii ENSMEUG00000003794 59463 Myotis lucifugus ENSMLUG00000012927
61853 Nomascus leucogenys ENSNLEG00000007981 9258 Ornithorhynchus anatinus ENSOANG00000003082
30611 Otolemur garnettii ENSOGAG00000005735 9978 Ochotona princeps ENSOPRG00000016862
8090 Oryzias latipes ENSORLG00000015062 9601 Pongo abelii ENSPPYG00000009175
13735 Pelodiscus sinensis ENSPSIG00000014469 9598 Pan troglodytes ENSPTRG00000010040
10116 Rattus norvegicus ENSRNOG00000012405 9305 Sarcophilus harrisii ENSSHAG00000014955
9823 Sus scrofa ENSSSCG00000004535 43179 Ictidomys tridecemlineatus ENSSTOG00000005134
37347 Tupaia belangeri ENSTBEG00000015498 9478 Tarsius syrichta ENSTSYG00000009542
9739 Tursiops truncatus ENSTTRG00000011542 8364 Xenopus tropicalis ENSXETG00000019086
28377 Anolis carolinensis ENSACAG00000008863 9646 Ailuropoda melanoleuca ENSAMEG00000017162
51511 Ciona savignyi ENSCSAVG00000011705 69293 Gasterosteus aculeatus ENSGACG00000000628
9785 Loxodonta africana ENSLAFG00000013449 9544 Macaca mulatta ENSMMUG00000012001
9669 Mustela putorius furo ENSMPUG00000016460 132908 Pteropus vampyrus ENSPVAG00000002074
42254 Sorex araneus ENSSARG00000001666 99883 Tetraodon nigroviridis ENSTNIG00000010330
31033 Takifugu rubripes ENSTRUG00000002569