Basic Information
Gene ID 5456 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name POU3F4; BRN4, OTF9
Full Name POU domain, class 3, transcription factor 4
Organism Homo sapiens [9606]

Cross Reference
UniProt P49335 UniGene Hs.2229
PDB NULL OMIM 304400
KEGG hsa:5456 UCSC uc004eeg.2

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING 9606.ENSP00000362296

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000362296 Gene3D G3DSA:1.10.10.60 IPR009057 260 335 2.90e-22 Homeodomain-like
ENSP00000362296 Gene3D G3DSA:1.10.260.40 IPR010982 192 259 3.20e-41 Lambda repressor-like, DNA-binding domain
ENSP00000362296 Pfam PF00046 IPR001356 279 335 9.00e-18 Homeobox domain
ENSP00000362296 Pfam PF00157 IPR000327 187 260 1.20e-39 POU-specific
ENSP00000362296 PIRSF PIRSF002629 IPR016362 1 359 5.60e-188 Transcription factor, homeobox/POU
ENSP00000362296 PRINTS PR00028 IPR013847 205 222 4.00e-46 POU domain
ENSP00000362296 PRINTS PR00028 IPR013847 228 241 4.00e-46 POU domain
ENSP00000362296 PRINTS PR00028 IPR013847 244 259 4.00e-46 POU domain
ENSP00000362296 PRINTS PR00028 IPR013847 277 297 4.00e-46 POU domain
ENSP00000362296 PRINTS PR00028 IPR013847 312 327 4.00e-46 POU domain
ENSP00000362296 ProSitePatterns PS00027 IPR017970 311 334 - Homeobox, conserved site
ENSP00000362296 ProSitePatterns PS00035 IPR000327 204 216 - POU-specific
ENSP00000362296 ProSitePatterns PS00465 IPR000327 228 241 - POU-specific
ENSP00000362296 ProSiteProfiles PS50071 IPR001356 276 336 0.00e-00 Homeobox domain
ENSP00000362296 ProSiteProfiles PS51179 IPR000327 186 260 0.00e-00 POU-specific
ENSP00000362296 SMART SM00352 IPR000327 186 260 1.40e-55 POU-specific
ENSP00000362296 SMART SM00389 IPR001356 278 340 3.60e-21 Homeobox domain
ENSP00000362296 SUPERFAMILY SSF46689 IPR009057 264 336 0.00e-00 Homeodomain-like
ENSP00000362296 SUPERFAMILY SSF47413 IPR010982 187 260 0.00e-00 Lambda repressor-like, DNA-binding domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000362296 PF00157 7e-40 Pou Pou domain - N-terminal to homeobox domain
ENSP00000362296 PF00046 2.7e-18 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000362296 GO:0006351 biological_process transcription, DNA-templated
ENSP00000362296 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSP00000362296 GO:0007275 biological_process multicellular organismal development
ENSP00000362296 GO:0005634 cellular_component nucleus
ENSP00000362296 GO:0003677 molecular_function DNA binding
ENSP00000362296 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000362296 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9823 Sus scrofa 100152446 7029 Acyrthosiphon pisum 100168140
9685 Felis catus 101093920 9796 Equus caballus 100071720
7425 Nasonia vitripennis 100120876 10224 Saccoglossus kowalevskii 100313563
9986 Oryctolagus cuniculus 100347010 9601 Pongo abelii 100437998
9646 Ailuropoda melanoleuca 100472065 30195 Bombus terrestris 100649181
9785 Loxodonta africana 100654602 8128 Oreochromis niloticus 100692750
10029 Cricetulus griseus 100756260 7463 Apis florea 100872962
143995 Megachile rotundata 100877565 34638 Metaseiulus occidentalis 100901607
9597 Pan paniscus 100995218 9555 Papio anubis 100997936
39432 Saimiri boliviensis 101035929 31033 Takifugu rubripes 101070138
8090 Oryzias latipes 101164903 9669 Mustela putorius furo 101686361
43179 Ictidomys tridecemlineatus 101967578 7897 Latimeria chalumnae 102365603
59463 Myotis lucifugus 102438356 13735 Pelodiscus sinensis 102451842
6239 Caenorhabditis elegans 172640 7955 Danio rerio 30397
7227 Drosophila melanogaster 38752 7460 Apis mellifera 410203
9913 Bos taurus 539732 7668 Strongylocentrotus purpuratus 577601
9544 Macaca mulatta 710157 28377 Anolis carolinensis ENSACAG00000023192
9615 Canis familiaris ENSCAFG00000029595 9358 Choloepus hoffmanni ENSCHOG00000002799
9483 Callithrix jacchus ENSCJAG00000002526 10141 Cavia porcellus ENSCPOG00000003373
10020 Dipodomys ordii ENSDORG00000006273 9371 Echinops telfairi ENSETEG00000020341
69293 Gasterosteus aculeatus ENSGACG00000018547 9595 Gorilla gorilla ENSGGOG00000028066
8049 Gadus morhua ENSGMOG00000020044 9103 Meleagris gallopavo ENSMGAG00000002765
13616 Monodelphis domestica ENSMODG00000014279 9258 Ornithorhynchus anatinus ENSOANG00000002241
30611 Otolemur garnettii ENSOGAG00000028714 9813 Procavia capensis ENSPCAG00000008737
9598 Pan troglodytes ENSPTRG00000029496 132908 Pteropus vampyrus ENSPVAG00000001305
10116 Rattus norvegicus ENSRNOG00000006908 9305 Sarcophilus harrisii ENSSHAG00000017944
99883 Tetraodon nigroviridis ENSTNIG00000015773 30538 Vicugna pacos ENSVPAG00000010779
8364 Xenopus tropicalis ENSXETG00000014504 8083 Xiphophorus maculatus ENSXMAG00000011836
7070 Tribolium castaneum 656764 9361 Dasypus novemcinctus ENSDNOG00000004912
30608 Microcebus murinus ENSMICG00000017301 9978 Ochotona princeps ENSOPRG00000012834