Basic Information
Gene ID 728340 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name GTF2H2; BTF2P44
Full Name General transcription factor IIH subunit 2
Organism Homo sapiens [9606]

Cross Reference
UniProt Q13888 UniGene Hs.607501
PDB 1Z60 OMIM 601748
KEGG hsa:728340 UCSC uc003kau.4

Protein Interactions
DIP DIP-786N
IntAct Q13888
MINT MINT-3028823
STRING 9606.ENSP00000274400

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000274400 Gene3D G3DSA:3.40.50.410 IPR002035 60 233 1.80e-05 von Willebrand factor, type A
ENSP00000274400 PANTHER PTHR12695 IPR012170 1 395 0.00e-00 TFIIH subunit Ssl1/p44
ENSP00000274400 Pfam PF04056 IPR007198 64 255 1.30e-94 Ssl1-like
ENSP00000274400 Pfam PF07975 IPR004595 344 386 1.40e-15 TFIIH C1-like domain
ENSP00000274400 PIRSF PIRSF015919 IPR012170 2 388 4.10e-246 TFIIH subunit Ssl1/p44
ENSP00000274400 ProSitePatterns PS00028 IPR007087 360 380 - Zinc finger, C2H2
ENSP00000274400 ProSiteProfiles PS50234 IPR002035 60 236 0.00e-00 von Willebrand factor, type A
ENSP00000274400 SMART SM00327 IPR002035 58 233 6.40e-17 von Willebrand factor, type A
ENSP00000274400 SMART SM01047 IPR004595 344 387 4.00e-25 TFIIH C1-like domain
ENSP00000274400 TIGRFAM TIGR00622 IPR012170 288 388 8.90e-50 TFIIH subunit Ssl1/p44

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000274400 PF04056 0 Ssl1 Ssl1-like
ENSP00000274400 PF07975 1.4e-15 C1_4 TFIIH C1-like domain
ENSP00000274400 PF13519 1e-14 VWA_2 von Willebrand factor type A domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000274400 GO:0006289 biological_process nucleotide-excision repair
ENSP00000274400 GO:0000439 cellular_component core TFIIH complex
ENSP00000274400 GO:0008270 molecular_function zinc ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9258 Ornithorhynchus anatinus 100081699 7425 Nasonia vitripennis 100114652
7029 Acyrthosiphon pisum 100162535 400682 Amphimedon queenslandica 100636837
30195 Bombus terrestris 100649692 132113 Bombus impatiens 100743113
10029 Cricetulus griseus 100771702 7463 Apis florea 100872643
143995 Megachile rotundata 100877837 9305 Sarcophilus harrisii 100934072
30611 Otolemur garnettii 100959995 9597 Pan paniscus 100987487
9555 Papio anubis 101013583 39432 Saimiri boliviensis 101052010
31033 Takifugu rubripes 101071539 43179 Ictidomys tridecemlineatus 101957203
7897 Latimeria chalumnae 102353559 13735 Pelodiscus sinensis 102446125
10090 Mus musculus 23894 7227 Drosophila melanogaster 40509
7460 Apis mellifera 411526 9598 Pan troglodytes 461830
7668 Strongylocentrotus purpuratus 589616 9544 Macaca mulatta 700737
9913 Bos taurus ENSBTAG00000027983 7719 Ciona intestinalis ENSCING00000000752
9483 Callithrix jacchus ENSCJAG00000016246 10141 Cavia porcellus ENSCPOG00000005775
9371 Echinops telfairi ENSETEG00000003921 9685 Felis catus ENSFCAG00000028495
69293 Gasterosteus aculeatus ENSGACG00000003759 9031 Gallus gallus ENSGALG00000002399
8049 Gadus morhua ENSGMOG00000005686 9785 Loxodonta africana ENSLAFG00000010244
59463 Myotis lucifugus ENSMLUG00000007994 13616 Monodelphis domestica ENSMODG00000025598
9669 Mustela putorius furo ENSMPUG00000014474 8090 Oryzias latipes ENSORLG00000017264
9813 Procavia capensis ENSPCAG00000011062 132908 Pteropus vampyrus ENSPVAG00000013516
9823 Sus scrofa ENSSSCG00000028786 37347 Tupaia belangeri ENSTBEG00000015248
59729 Taeniopygia guttata ENSTGUG00000001554 99883 Tetraodon nigroviridis ENSTNIG00000004548
9739 Tursiops truncatus ENSTTRG00000002883 8364 Xenopus tropicalis ENSXETG00000026187

Paralogs
730394