Basic Information
Gene ID 8553 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name BHLHE40; BHLHB2, DEC1, SHARP2, STRA13
Full Name Class E basic helix-loop-helix protein 40
Organism Homo sapiens [9606]

Cross Reference
UniProt O14503 UniGene Hs.744856
PDB NULL OMIM 604256
KEGG hsa:8553 UCSC uc003bqf.3

Protein Interactions
DIP DIP-36698N
IntAct O14503
MINT MINT-1374397
STRING 9606.ENSP00000256495

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000256495 Gene3D G3DSA:4.10.280.10 IPR011598 51 110 3.50e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000256495 Pfam PF00010 IPR011598 57 107 8.70e-12 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000256495 Pfam PF07527 IPR003650 140 181 2.80e-10 Orange
ENSP00000256495 ProSiteProfiles PS50888 IPR011598 52 107 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000256495 ProSiteProfiles PS51054 IPR003650 142 175 0.00e-00 Orange
ENSP00000256495 SMART SM00353 IPR011598 58 113 8.30e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSP00000256495 SMART SM00511 IPR018352 140 184 2.30e-15 Orange subgroup
ENSP00000256495 SUPERFAMILY SSF47459 IPR011598 49 124 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000256495 PF00010 4.4e-12 HLH Helix-loop-helix DNA-binding domain
ENSP00000256495 PF07527 1.2e-10 Hairy_orange Hairy Orange

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
31033 Takifugu rubripes 101071529 8090 Oryzias latipes 100049309
9646 Ailuropoda melanoleuca 100467414 9823 Sus scrofa 100514873
61853 Nomascus leucogenys 100588063 8128 Oreochromis niloticus 100703692
10029 Cricetulus griseus 100765325 9555 Papio anubis 101017675
39432 Saimiri boliviensis 101028697 9685 Felis catus 101101625
9595 Gorilla gorilla 101151761 9669 Mustela putorius furo 101679295
43179 Ictidomys tridecemlineatus 101963057 8083 Xiphophorus maculatus 102223765
13735 Pelodiscus sinensis 102462779 10090 Mus musculus 20893
9598 Pan troglodytes 460136 9615 Canis familiaris 484680
9544 Macaca mulatta 707083 9358 Choloepus hoffmanni ENSCHOG00000002253
10141 Cavia porcellus ENSCPOG00000004014 7955 Danio rerio ENSDARG00000004060
10020 Dipodomys ordii ENSDORG00000006908 9371 Echinops telfairi ENSETEG00000005461
69293 Gasterosteus aculeatus ENSGACG00000000659 8049 Gadus morhua ENSGMOG00000002353
7897 Latimeria chalumnae ENSLACG00000001814 9315 Macropus eugenii ENSMEUG00000010801
30608 Microcebus murinus ENSMICG00000011495 9986 Oryctolagus cuniculus ENSOCUG00000015177
9978 Ochotona princeps ENSOPRG00000000735 9813 Procavia capensis ENSPCAG00000005404
9601 Pongo abelii ENSPPYG00000013696 132908 Pteropus vampyrus ENSPVAG00000007723
10116 Rattus norvegicus ENSRNOG00000007152 59729 Taeniopygia guttata ENSTGUG00000010301
99883 Tetraodon nigroviridis ENSTNIG00000014553 9478 Tarsius syrichta ENSTSYG00000002535
9739 Tursiops truncatus ENSTTRG00000002786 8364 Xenopus tropicalis ENSXETG00000005207