Basic Information
Gene ID 9971 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name NR1H4; BAR, FXR, HRR1, RIP14
Full Name Bile acid receptor
Organism Homo sapiens [9606]

Cross Reference
UniProt Q96RI1 UniGene Hs.732506
PDB 4II6 OMIM 603826
KEGG hsa:9971 UCSC uc001tht.2

Protein Interactions
DIP DIP-39370N
IntAct Q96RI1
MINT NULL
STRING 9606.ENSP00000315442

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000447149 Gene3D G3DSA:1.10.565.10 IPR008946 193 252 6.30e-70 Nuclear hormone receptor, ligand-binding
ENSP00000447149 Gene3D G3DSA:1.10.565.10 IPR008946 293 485 6.30e-70 Nuclear hormone receptor, ligand-binding
ENSP00000447149 Gene3D G3DSA:3.30.50.10 IPR013088 134 192 1.40e-26 Zinc finger, NHR/GATA-type
ENSP00000447149 Pfam PF00104 IPR000536 290 463 1.30e-34 Nuclear hormone receptor, ligand-binding, core
ENSP00000447149 Pfam PF00105 IPR001628 136 202 9.00e-29 Zinc finger, nuclear hormone receptor-type
ENSP00000447149 PRINTS PR00047 IPR001628 137 153 6.60e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000447149 PRINTS PR00047 IPR001628 153 168 6.60e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000447149 PRINTS PR00047 IPR001628 186 194 6.60e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000447149 PRINTS PR00047 IPR001628 194 202 6.60e-18 Zinc finger, nuclear hormone receptor-type
ENSP00000447149 PRINTS PR00398 IPR001723 304 325 2.10e-18 Steroid hormone receptor
ENSP00000447149 PRINTS PR00398 IPR001723 325 341 2.10e-18 Steroid hormone receptor
ENSP00000447149 PRINTS PR00398 IPR001723 389 404 2.10e-18 Steroid hormone receptor
ENSP00000447149 PRINTS PR00398 IPR001723 446 463 2.10e-18 Steroid hormone receptor
ENSP00000447149 PRINTS PR00546 IPR001728 125 139 4.10e-12 Thyroid hormone receptor
ENSP00000447149 PRINTS PR00546 IPR001728 301 322 4.10e-12 Thyroid hormone receptor
ENSP00000447149 PRINTS PR00546 IPR001728 327 346 4.10e-12 Thyroid hormone receptor
ENSP00000447149 PRINTS PR00546 IPR001728 389 411 4.10e-12 Thyroid hormone receptor
ENSP00000447149 ProSitePatterns PS00031 IPR001628 137 163 - Zinc finger, nuclear hormone receptor-type
ENSP00000447149 ProSiteProfiles PS51030 IPR001628 134 209 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSP00000447149 SMART SM00399 IPR001628 134 205 6.40e-40 Zinc finger, nuclear hormone receptor-type
ENSP00000447149 SMART SM00430 IPR000536 303 458 6.30e-36 Nuclear hormone receptor, ligand-binding, core
ENSP00000447149 SUPERFAMILY SSF48508 IPR008946 259 485 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000447149 PF00104 7.2e-35 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSP00000447149 PF00105 9e-29 zf-C4 Zinc finger, C4 type (two domains)

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9823 Sus scrofa 100153960 31033 Takifugu rubripes 101078607
9615 Canis familiaris 612928 7425 Nasonia vitripennis 100119033
7029 Acyrthosiphon pisum 100160393 59729 Taeniopygia guttata 100219563
10224 Saccoglossus kowalevskii 100313647 61853 Nomascus leucogenys 100587301
30195 Bombus terrestris 100646757 8128 Oreochromis niloticus 100702741
132113 Bombus impatiens 100749603 10029 Cricetulus griseus 100763600
7463 Apis florea 100872217 143995 Megachile rotundata 100883359
34638 Metaseiulus occidentalis 100908536 9597 Pan paniscus 100992986
9555 Papio anubis 100997959 39432 Saimiri boliviensis 101030117
8090 Oryzias latipes 101166124 9669 Mustela putorius furo 101671585
8083 Xiphophorus maculatus 102235217 59463 Myotis lucifugus 102430686
10090 Mus musculus 22259 7227 Drosophila melanogaster 35540
9031 Gallus gallus 373902 7460 Apis mellifera 406084
7668 Strongylocentrotus purpuratus 574588 10116 Rattus norvegicus 58852
7070 Tribolium castaneum 657515 9544 Macaca mulatta 695618
28377 Anolis carolinensis ENSACAG00000012333 9646 Ailuropoda melanoleuca ENSAMEG00000015232
9913 Bos taurus ENSBTAG00000013596 9358 Choloepus hoffmanni ENSCHOG00000013215
7719 Ciona intestinalis ENSCING00000007203 9483 Callithrix jacchus ENSCJAG00000002087
10141 Cavia porcellus ENSCPOG00000002168 51511 Ciona savignyi ENSCSAVG00000007313
10020 Dipodomys ordii ENSDORG00000001224 9365 Erinaceus europaeus ENSEEUG00000012218
9371 Echinops telfairi ENSETEG00000019430 9685 Felis catus ENSFCAG00000006469
69293 Gasterosteus aculeatus ENSGACG00000011745 9595 Gorilla gorilla ENSGGOG00000008137
9315 Macropus eugenii ENSMEUG00000009703 30608 Microcebus murinus ENSMICG00000013522
13616 Monodelphis domestica ENSMODG00000004996 9978 Ochotona princeps ENSOPRG00000010997
9813 Procavia capensis ENSPCAG00000006718 9601 Pongo abelii ENSPPYG00000004867
13735 Pelodiscus sinensis ENSPSIG00000005774 9598 Pan troglodytes ENSPTRG00000003560
42254 Sorex araneus ENSSARG00000004689 43179 Ictidomys tridecemlineatus ENSSTOG00000011771
37347 Tupaia belangeri ENSTBEG00000016715 99883 Tetraodon nigroviridis ENSTNIG00000012144
9478 Tarsius syrichta ENSTSYG00000002997 9739 Tursiops truncatus ENSTTRG00000016373
30538 Vicugna pacos ENSVPAG00000006065 7955 Danio rerio ENSDARG00000057741
9796 Equus caballus ENSECAG00000018166 8049 Gadus morhua ENSGMOG00000003773
7897 Latimeria chalumnae ENSLACG00000017655 9785 Loxodonta africana ENSLAFG00000028744
9258 Ornithorhynchus anatinus ENSOANG00000005583 9986 Oryctolagus cuniculus ENSOCUG00000007177
30611 Otolemur garnettii ENSOGAG00000007874 132908 Pteropus vampyrus ENSPVAG00000014680
9305 Sarcophilus harrisii ENSSHAG00000010518 8364 Xenopus tropicalis ENSXETG00000030372