Basic Information
Gene ID ENSAMEG00000006061
Gene Name STAT5B
Full Name Signal transducer and activator of transcription
Organism Ailuropoda melanoleuca [9646]

Cross Reference
UniProt G1LHK6 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSAMEP00000006402 Gene3D G3DSA:1.10.238.10 IPR011992 469 594 1.40e-47 EF-hand domain pair
ENSAMEP00000006402 Gene3D G3DSA:1.10.532.10 IPR013799 1 125 5.50e-48 STAT transcription factor, protein interaction
ENSAMEP00000006402 Gene3D G3DSA:1.20.1050.20 IPR013800 139 186 3.00e-10 STAT transcription factor, all-alpha
ENSAMEP00000006402 Gene3D G3DSA:2.60.40.630 IPR012345 330 468 5.90e-69 STAT transcription factor, DNA-binding, subdomain
ENSAMEP00000006402 Gene3D G3DSA:3.30.505.10 IPR000980 595 709 7.90e-39 SH2 domain
ENSAMEP00000006402 PANTHER PTHR11801 IPR001217 2 776 0.00e-00 Transcription factor STAT
ENSAMEP00000006402 Pfam PF00017 IPR000980 592 640 4.70e-10 SH2 domain
ENSAMEP00000006402 Pfam PF01017 IPR013800 138 179 3.40e-07 STAT transcription factor, all-alpha
ENSAMEP00000006402 Pfam PF02864 IPR013801 329 580 4.10e-99 STAT transcription factor, DNA-binding
ENSAMEP00000006402 Pfam PF02865 IPR013799 2 125 4.60e-47 STAT transcription factor, protein interaction
ENSAMEP00000006402 ProSiteProfiles PS50001 IPR000980 586 688 0.00e-00 SH2 domain
ENSAMEP00000006402 SMART SM00252 IPR000980 584 702 1.70e-06 SH2 domain
ENSAMEP00000006402 SMART SM00964 IPR013799 2 126 3.10e-65 STAT transcription factor, protein interaction
ENSAMEP00000006402 SUPERFAMILY SSF47655 IPR015988 136 186 0.00e-00 STAT transcription factor, coiled coil
ENSAMEP00000006402 SUPERFAMILY SSF48092 IPR013799 1 124 0.00e-00 STAT transcription factor, protein interaction
ENSAMEP00000006402 SUPERFAMILY SSF49417 IPR008967 326 581 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSAMEP00000006402 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSAMEP00000006402 PF02865 0 STAT_int STAT protein, protein interaction domain
ENSAMEP00000006402 PF00017 1.7e-11 SH2 SH2 domain
ENSAMEP00000006402 PF01017 1.4e-07 STAT_alpha STAT protein, all-alpha domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSAMEP00000006402 GO:0001553 biological_process luteinization
ENSAMEP00000006402 GO:0001779 biological_process natural killer cell differentiation
ENSAMEP00000006402 GO:0006351 biological_process transcription, DNA-templated
ENSAMEP00000006402 GO:0007259 biological_process JAK-STAT cascade
ENSAMEP00000006402 GO:0007565 biological_process female pregnancy
ENSAMEP00000006402 GO:0007595 biological_process lactation
ENSAMEP00000006402 GO:0019218 biological_process regulation of steroid metabolic process
ENSAMEP00000006402 GO:0019915 biological_process lipid storage
ENSAMEP00000006402 GO:0030155 biological_process regulation of cell adhesion
ENSAMEP00000006402 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSAMEP00000006402 GO:0038161 biological_process prolactin signaling pathway
ENSAMEP00000006402 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSAMEP00000006402 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSAMEP00000006402 GO:0043029 biological_process T cell homeostasis
ENSAMEP00000006402 GO:0043066 biological_process negative regulation of apoptotic process
ENSAMEP00000006402 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSAMEP00000006402 GO:0045579 biological_process positive regulation of B cell differentiation
ENSAMEP00000006402 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSAMEP00000006402 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSAMEP00000006402 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSAMEP00000006402 GO:0046543 biological_process development of secondary female sexual characteristics
ENSAMEP00000006402 GO:0050729 biological_process positive regulation of inflammatory response
ENSAMEP00000006402 GO:0005634 cellular_component nucleus
ENSAMEP00000006402 GO:0005737 cellular_component cytoplasm
ENSAMEP00000006402 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSAMEP00000006402 GO:0004871 molecular_function signal transducer activity
ENSAMEP00000006402 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
13616 Monodelphis domestica 100012174 7425 Nasonia vitripennis 100121885
7029 Acyrthosiphon pisum 100161101 6087 Hydra magnipapillata 100206878
9601 Pongo abelii 100462537 400682 Amphimedon queenslandica 100641588
30195 Bombus terrestris 100647789 132113 Bombus impatiens 100743540
10029 Cricetulus griseus 100755571 7463 Apis florea 100864112
34638 Metaseiulus occidentalis 100907258 30611 Otolemur garnettii 100958999
9597 Pan paniscus 100989105 39432 Saimiri boliviensis 101043203
9669 Mustela putorius furo 101691575 9031 Gallus gallus 395556
7227 Drosophila melanogaster 42428 9544 Macaca mulatta 574129
7668 Strongylocentrotus purpuratus 576433 7719 Ciona intestinalis 778770
28377 Anolis carolinensis ENSACAG00000009680 9986 Oryctolagus cuniculus 100348267
143995 Megachile rotundata 100880948 9555 Papio anubis 101000002
10090 Mus musculus 20851 10116 Rattus norvegicus 25126
9823 Sus scrofa 397340 7460 Apis mellifera 413742
7070 Tribolium castaneum 657965 9358 Choloepus hoffmanni ENSCHOG00000005387
10141 Cavia porcellus ENSCPOG00000026466 51511 Ciona savignyi ENSCSAVG00000011110
7955 Danio rerio ENSDARG00000019392 9796 Equus caballus ENSECAG00000007847
9365 Erinaceus europaeus ENSEEUG00000003642 9371 Echinops telfairi ENSETEG00000008528
69293 Gasterosteus aculeatus ENSGACG00000008634 9785 Loxodonta africana ENSLAFG00000014055
9315 Macropus eugenii ENSMEUG00000006640 9978 Ochotona princeps ENSOPRG00000008312
13735 Pelodiscus sinensis ENSPSIG00000015138 9598 Pan troglodytes ENSPTRG00000009198
43179 Ictidomys tridecemlineatus ENSSTOG00000006691 99883 Tetraodon nigroviridis ENSTNIG00000011707
8083 Xiphophorus maculatus ENSXMAG00000005165 9913 Bos taurus ENSBTAG00000009496
9615 Canis familiaris ENSCAFG00000015509 9483 Callithrix jacchus ENSCJAG00000000426
9361 Dasypus novemcinctus ENSDNOG00000007398 10020 Dipodomys ordii ENSDORG00000000303
9685 Felis catus ENSFCAG00000028112 9595 Gorilla gorilla ENSGGOG00000008216
8049 Gadus morhua ENSGMOG00000014154 7897 Latimeria chalumnae ENSLACG00000002646
9103 Meleagris gallopavo ENSMGAG00000003430 30608 Microcebus murinus ENSMICG00000011988
59463 Myotis lucifugus ENSMLUG00000012050 61853 Nomascus leucogenys ENSNLEG00000011444
9258 Ornithorhynchus anatinus ENSOANG00000006496 8128 Oreochromis niloticus ENSONIG00000007261
8090 Oryzias latipes ENSORLG00000003961 9813 Procavia capensis ENSPCAG00000010107
7757 Petromyzon marinus ENSPMAG00000009008 132908 Pteropus vampyrus ENSPVAG00000003876
42254 Sorex araneus ENSSARG00000014205 37347 Tupaia belangeri ENSTBEG00000009608
59729 Taeniopygia guttata ENSTGUG00000002572 31033 Takifugu rubripes ENSTRUG00000015454
9478 Tarsius syrichta ENSTSYG00000000267 9739 Tursiops truncatus ENSTTRG00000006684
30538 Vicugna pacos ENSVPAG00000005450 8364 Xenopus tropicalis ENSXETG00000000836