Basic Information
Gene ID ENSFCAG00000013629
Gene Name EPAS1
Full Name Uncharacterized protein
Organism Felis catus [9685]

Cross Reference
UniProt M3WJ68 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSFCAP00000012637 Pfam PF08778 IPR014887 827 866 2.10e-20 HIF-1 alpha, transactivation domain, C-terminal
ENSFCAP00000012637 Pfam PF11413 IPR021537 516 548 1.80e-17 Hypoxia-inducible factor, alpha subunit
ENSFCAP00000012637 PRINTS PR00785 IPR001067 101 120 9.10e-07 Nuclear translocator
ENSFCAP00000012637 PRINTS PR00785 IPR001067 243 260 9.10e-07 Nuclear translocator
ENSFCAP00000012637 PRINTS PR00785 IPR001067 49 69 9.10e-07 Nuclear translocator
ENSFCAP00000012637 ProSiteProfiles PS50112 IPR000014 249 300 0.00e-00 PAS domain
ENSFCAP00000012637 ProSiteProfiles PS50112 IPR000014 84 147 0.00e-00 PAS domain
ENSFCAP00000012637 ProSiteProfiles PS50888 IPR011598 14 67 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSFCAP00000012637 SMART SM00086 IPR001610 304 347 2.20e-11 PAC motif
ENSFCAP00000012637 SMART SM00091 IPR000014 232 298 3.70e-10 PAS domain
ENSFCAP00000012637 SMART SM00091 IPR000014 86 152 1.50e-11 PAS domain
ENSFCAP00000012637 SMART SM00353 IPR011598 20 75 1.30e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSFCAP00000012637 SUPERFAMILY SSF47459 IPR011598 11 72 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSFCAP00000012637 SUPERFAMILY SSF55785 IPR000014 244 346 0.00e-00 PAS domain
ENSFCAP00000012637 SUPERFAMILY SSF55785 IPR000014 95 201 0.00e-00 PAS domain
ENSFCAP00000012637 TIGRFAM TIGR00229 IPR000014 252 328 4.70e-08 PAS domain
ENSFCAP00000012637 TIGRFAM TIGR00229 IPR000014 98 150 1.10e-05 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSFCAP00000012637 PF14598 2.1e-28 PAS_11 PAS domain
ENSFCAP00000012637 PF08447 4e-25 PAS_3 PAS fold
ENSFCAP00000012637 PF08778 1e-20 HIF-1a_CTAD HIF-1 alpha C terminal transactivation domain
ENSFCAP00000012637 PF11413 8.6e-18 HIF-1 Hypoxia-inducible factor-1
ENSFCAP00000012637 PF00989 4.2e-14 PAS PAS fold
ENSFCAP00000012637 PF13426 9.1e-11 PAS_9 PAS domain
ENSFCAP00000012637 PF08448 1.6e-07 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSFCAP00000012637 GO:0001666 biological_process response to hypoxia
ENSFCAP00000012637 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSFCAP00000012637 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSFCAP00000012637 GO:0071456 biological_process cellular response to hypoxia
ENSFCAP00000012637 GO:0005634 cellular_component nucleus
ENSFCAP00000012637 GO:0005737 cellular_component cytoplasm
ENSFCAP00000012637 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSFCAP00000012637 GO:0004871 molecular_function signal transducer activity
ENSFCAP00000012637 GO:0035035 molecular_function histone acetyltransferase binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9361 Dasypus novemcinctus ENSDNOG00000005938 9483 Callithrix jacchus 100396711
9597 Pan paniscus 100975248 39432 Saimiri boliviensis 101052563
9669 Mustela putorius furo 101679355 7897 Latimeria chalumnae 102357464
13735 Pelodiscus sinensis 102453156 9606 Homo sapiens 2034
9646 Ailuropoda melanoleuca ENSAMEG00000006020 9913 Bos taurus ENSBTAG00000003711
9615 Canis familiaris ENSCAFG00000002627 9358 Choloepus hoffmanni ENSCHOG00000005351
10141 Cavia porcellus ENSCPOG00000014242 7955 Danio rerio ENSDARG00000057671
10020 Dipodomys ordii ENSDORG00000003635 9796 Equus caballus ENSECAG00000014594
9365 Erinaceus europaeus ENSEEUG00000012802 69293 Gasterosteus aculeatus ENSGACG00000011414
9031 Gallus gallus ENSGALG00000010005 8049 Gadus morhua ENSGMOG00000016337
9785 Loxodonta africana ENSLAFG00000012361 9315 Macropus eugenii ENSMEUG00000004035
9103 Meleagris gallopavo ENSMGAG00000010293 30608 Microcebus murinus ENSMICG00000002949
59463 Myotis lucifugus ENSMLUG00000007093 9544 Macaca mulatta ENSMMUG00000023326
13616 Monodelphis domestica ENSMODG00000000953 9986 Oryctolagus cuniculus ENSOCUG00000014904
30611 Otolemur garnettii ENSOGAG00000008084 9978 Ochotona princeps ENSOPRG00000010205
9813 Procavia capensis ENSPCAG00000014714 132908 Pteropus vampyrus ENSPVAG00000011259
10116 Rattus norvegicus ENSRNOG00000021318 9823 Sus scrofa ENSSSCG00000008443
43179 Ictidomys tridecemlineatus ENSSTOG00000012628 37347 Tupaia belangeri ENSTBEG00000004645
59729 Taeniopygia guttata ENSTGUG00000003933 99883 Tetraodon nigroviridis ENSTNIG00000009866
31033 Takifugu rubripes ENSTRUG00000005627 9478 Tarsius syrichta ENSTSYG00000001312
9739 Tursiops truncatus ENSTTRG00000011883 8364 Xenopus tropicalis ENSXETG00000026167
8083 Xiphophorus maculatus ENSXMAG00000004970